Optical imaging of voltage and calcium in cardiac cells & tissues.

Circulation Research
Todd J HerronJosé Jalife

Abstract

Cardiac optical mapping has proven to be a powerful technology for studying cardiovascular function and disease. The development and scientific impact of this methodology are well-documented. Because of its relevance in cardiac research, this imaging technology advances at a rapid pace. Here, we review technological and scientific developments during the past several years and look toward the future. First, we explore key components of a modern optical mapping set-up, focusing on: (1) new camera technologies; (2) powerful light-emitting-diodes (from ultraviolet to red) for illumination; (3) improved optical filter technology; (4) new synthetic and optogenetic fluorescent probes; (5) optical mapping with motion and contraction; (6) new multiparametric optical mapping techniques; and (7) photon scattering effects in thick tissue preparations. We then look at recent optical mapping studies in single cells, cardiomyocyte monolayers, atria, and whole hearts. Finally, we briefly look into the possible future roles of optical mapping in the development of regenerative cardiac research, cardiac cell therapies, and molecular genetic advances.

References

Jul 1, 1979·The Journal of Physiology·M Morad, G Salama
Jan 1, 1978·Reviews of Physiology, Biochemistry and Pharmacology·L B Cohen, B M Salzberg
Sep 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·V Lev-Ram, A Grinvald
Jan 1, 1989·Annual Review of Neuroscience·R Y Tsien
Nov 1, 1987·Circulation Research·D C MichaelsJ Jalife
Aug 1, 1995·Pflügers Archiv : European journal of physiology·H WindischD Platzer
Sep 1, 1995·The American Journal of Physiology·B I BrombergJ P Boineau
Apr 1, 1994·Pflügers Archiv : European journal of physiology·P SchafferH Windisch
Aug 1, 1993·Journal of Cardiovascular Electrophysiology·E G Lakatta, T Guarnieri
Apr 1, 1996·Circulation Research·M A Laflamme, P L Becker
Feb 18, 1997·Circulation·R A GrayJ Jalife
Jun 6, 1998·The Journal of Physiology·Y K Ju, D G Allen
Aug 26, 1998·Proceedings of the National Academy of Sciences of the United States of America·G BubA Shrier
Apr 8, 1999·European Biophysics Journal : EBJ·J DomkeM Radmacher
Nov 30, 1999·Circulation Research·I BanvilleW M Smith
May 29, 2000·Journal of Cardiovascular Electrophysiology·V G Fast, R E Ideker
Aug 19, 2000·Circulation Research·D M Bers
Sep 7, 2000·Cardiovascular Research·M R BoyettI Kodama
Feb 13, 2001·Biophysical Journal·W T BaxterA M Pertsov
Apr 12, 2001·American Journal of Physiology. Heart and Circulatory Physiology·K R Laurita, A Singal

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Citations

Aug 14, 2012·Pflügers Archiv : European journal of physiology·Peter LeeChristian Bollensdorff
Aug 17, 2012·ACS Chemical Neuroscience·Hiroki MutohThomas Knöpfel
Nov 22, 2012·Proceedings of the National Academy of Sciences of the United States of America·Ping YanLeslie M Loew
May 29, 2012·American Journal of Physiology. Heart and Circulatory Physiology·Ronglih LiaoChee Chew Lim
Jul 24, 2012·American Journal of Physiology. Heart and Circulatory Physiology·Jacob I LaughnerIgor R Efimov
Oct 2, 2012·Circulation. Arrhythmia and Electrophysiology·Felipe AtienzaJosé Jalife
Aug 10, 2012·PloS One·Peter LeeChristopher E Woods
Jan 16, 2014·PloS One·Nele VandersickelAlexander V Panfilov
May 7, 2014·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Piero Colli FranzoneSimone Scacchi
Jul 31, 2014·Current Treatment Options in Cardiovascular Medicine·Jordan S Leyton-Mange, David J Milan
Dec 3, 2013·Canadian Journal of Physiology and Pharmacology·Sreejit ParameswaranRajendra K Sharma
Mar 5, 2013·American Journal of Physiology. Heart and Circulatory Physiology·Emilia Entcheva
Feb 10, 2016·Differentiation; Research in Biological Diversity·Tim P KelderMonique R M Jongbloed
Feb 29, 2016·Cell Calcium·Todd J Herron
Feb 1, 2013·Revista Española De Cardiología·Leticia Fernández-FrieraBorja Ibáñez
Nov 13, 2012·Journal of Molecular and Cellular Cardiology·José M Di DiegoCharles Antzelevitch
Oct 31, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Herman D HimelNabil El-Sherif
Jul 15, 2015·Journal of Pharmacological and Toxicological Methods·Icilio Cavero, Henry Holzgrefe
Oct 26, 2013·IEEE Reviews in Biomedical Engineering·Bas J Boukens, Igor R Efimov
May 20, 2014·IEEE Transactions on Medical Imaging·Weiguang DingMirza Faisal Beg
Jun 21, 2015·Cellular and Molecular Life Sciences : CMLS·Merlijn J MeensHeather S Duffy
Aug 15, 2014·Progress in Biophysics and Molecular Biology·Pablo LamataVicente Grau
Sep 7, 2014·Progress in Biophysics and Molecular Biology·Peter Kohl, T Alexander Quinn
Mar 29, 2014·Stem Cell Reports·Sean P SheehyKevin Kit Parker
Oct 16, 2012·Biochimica Et Biophysica Acta·Bjarke JensenAntoon F M Moorman
Jul 19, 2014·Progress in Biophysics and Molecular Biology·Christina M AmbrosiEmilia Entcheva
Apr 4, 2015·The Review of Scientific Instruments·Angelo GaitasJosé Jalife
Jan 7, 2014·Journal of Molecular and Cellular Cardiology·Denis V AbramochkinAndre Kamkin
May 18, 2016·Journal of Pharmacological and Toxicological Methods·Graham T DempseyJoel M Kralj
Aug 6, 2016·Trends in Cardiovascular Medicine·Thomas A CsepeVadim V Fedorov
May 29, 2016·Journal of Pharmacological and Toxicological Methods·Icilio CaveroHenry Holzgrefe
Jun 10, 2016·Computers in Biology and Medicine·Agnieszka F SzymanskaZoran Nenadic
Jul 1, 2016·Cardiovascular Engineering and Technology·M BeheshtiK Umapathy
Sep 20, 2016·British Journal of Pharmacology·Luca SalaChristine L Mummery
Dec 21, 2016·Journal of Molecular Recognition : JMR·Martin PeslVladimir Rotrekl
Jul 29, 2016·Stem Cells Translational Medicine·Guihua JiangShaun M Kunisaki

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