Optical microspherical resonators for biomedical sensing.

Sensors
Silvia SoriaGiancarlo C Righini

Abstract

Optical resonators play an ubiquitous role in modern optics. A particular class of optical resonators is constituted by spherical dielectric structures, where optical rays are total internal reflected. Due to minimal reflection losses and to potentially very low material absorption, these guided modes, known as whispering gallery modes, can confer the resonator an exceptionally high quality factor Q, leading to high energy density, narrow resonant-wavelength lines and a lengthy cavity ringdown. These attractive characteristics make these miniaturized optical resonators especially suited as laser cavities and resonant filters, but also as very sensitive sensors. First, a brief analysis is presented of the characteristics of microspherical resonators, of their fabrication methods, and of the light coupling techniques. Then, we attempt to overview some of the recent advances in the development of microspherical biosensors, underlining a number of important applications in the biomedical field.

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Citations

Mar 19, 2013·Biosensors & Bioelectronics·Heath A HuckabayRobert C Dunn
Nov 2, 2014·Optics Letters·Marta S FerreiraOrlando Frazão
Nov 16, 2011·Advanced Materials·Gabriella CipparroneRoberto Bartolino
Feb 15, 2012·Optics Express·Vincent Michaud-BelleauClaudine Nì Allen
Jun 21, 2016·Sensors·Giancarlo C Righini, Silvia Soria
Mar 1, 2012·Sensors·Mahammad A HannanAini Hussain
Jul 22, 2016·Biosensors·Gualtiero Nunzi ContiSilvia Soria
Sep 14, 2017·Sensors·Weeratouch Pongruengkiat, Suejit Pechprasarn
Mar 19, 2020·Micromachines·Gabriele FrigentiSilvia Soria Huguet
Dec 11, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mihai BoniAngela Staicu
Dec 30, 2016·Light, Science & Applications·Marina MarianoJordi Martorell
Nov 15, 2018·Micromachines·Francesco ChiavaioliFrancesco Prudenzano
Oct 16, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Carol E SoteropulosHeather K Hunt

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Methods Mentioned

BETA
biosensors
biosensor
biosensing
protein folding
surface-enhanced Raman scattering
surface plasmon resonance

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