Optical monitoring of chemical processes in turbid biogenic liquid dispersions by Photon Density Wave spectroscopy

Analytical and Bioanalytical Chemistry
Roland HassOliver Reich

Abstract

In turbid biogenic liquid material, like blood or milk, quantitative optical analysis is often strongly hindered by multiple light scattering resulting from cells, particles, or droplets. Here, optical attenuation is caused by losses due to absorption as well as scattering of light. Fiber-based Photon Density Wave (PDW) spectroscopy is a very promising method for the precise measurement of the optical properties of such materials. They are expressed as absorption and reduced scattering coefficients (μ a and μ s', respectively) and are linked to the chemical composition and physical properties of the sample. As a process analytical technology, PDW spectroscopy can sense chemical and/or physical processes within such turbid biogenic liquids, providing new scientific insight and process understanding. Here, for the first time, several bioprocesses are analyzed by PDW spectroscopy and the resulting optical coefficients are discussed with respect to established mechanistic models of the chosen processes. As model systems, enzymatic casein coagulation in milk, temperature-induced starch hydrolysis in beer mash, and oxy- as well as deoxygenation of human donor blood were investigated by PDW spectroscopy. The findings indicate that als...Continue Reading

References

Mar 1, 1996·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·J B FishkinE Gratton
Aug 10, 2000·Neoplasia : an International Journal for Oncology Research·B J TrombergJ Butler
Jan 13, 2004·Journal of Biomedical Optics·JeeHyun ChoiEnrico Gratton
Feb 3, 2007·Journal of Colloid and Interface Science·S SandraDouglas G Dalgleish
Mar 10, 2010·Journal of Biomedical Optics·Biju CletusVincent Andrew McGlone
Sep 3, 2011·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Roland Hass, Oliver Reich
Jan 1, 1999·Journal of Biomedical Optics·A RogganG Mu Ller

❮ Previous
Next ❯

Citations

Oct 4, 2016·Analytical and Bioanalytical Chemistry·Marvin MünzbergOliver Reich
Mar 13, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Katharina BresselTim J Wooster

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.