Optical properties of human amniotic fluid: implications for videofetoscopic surgery

Fetal Diagnosis and Therapy
Shaun A SteigmanDario O Fauza

Abstract

Videofetoscopy typically demands the substitution of oft-turbid amniotic fluid with clear crystalloid. This maneuver can be cumbersome and may lead to complications. We sought to determine the optical properties of the amniotic fluid, as a pre-requisite for optimizing video image processing during videofetoscopy and eventually avoid amniotic fluid replacement. Human amniotic fluid samples (n = 21) were procured at 19-36 weeks of gestation. Optical refraction and reflection indices were recorded as percentages of light transmission through the fluid using an integrated spectrometer covering wavelengths of 400-950 nm, with 1.0 nm resolution. Statistical analysis was by one-way ANOVA (p < 0.05). Peak optical refraction fell within a relatively limited window of the near-infrared spectrum, at 848.1 +/- 52.3 nm, regardless of gestational age or overall light absorbance. Within the visible spectrum, transmission was highest at the highest wavelengths. A statistically significant inverse relationship existed between gestational age and overall light transmission. Light reflection was negligible in all samples. Light transmission through amniotic fluid is optimal in the near-infrared spectrum and at the highest visible wavelengths, reg...Continue Reading

Citations

Jul 14, 2012·Journal of Gastric Cancer·Kai Bickenbach, Vivian E Strong
Dec 22, 2020·International Journal of Computer Vision·François ChadebecqDanail Stoyanov

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