Optical-resolution photoacoustic endomicroscopy in vivo

Biomedical Optics Express
Joon-Mo YangLihong V Wang

Abstract

Optical-resolution photoacoustic microscopy (OR-PAM) has become a major experimental tool of photoacoustic tomography, with unique imaging capabilities for various biological applications. However, conventional imaging systems are all table-top embodiments, which preclude their use in internal organs. In this study, by applying the OR-PAM concept to our recently developed endoscopic technique, called photoacoustic endoscopy (PAE), we created an optical-resolution photoacoustic endomicroscopy (OR-PAEM) system, which enables internal organ imaging with a much finer resolution than conventional acoustic-resolution PAE systems. OR-PAEM has potential preclinical and clinical applications using either endogenous or exogenous contrast agents.

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Citations

Apr 14, 2016·Photoacoustics·Emmanuel Bossy, Sylvain Gigan
Jun 8, 2015·The Cancer Journal·Stephan Rogalla, Christopher H Contag
Jul 14, 2018·Journal of Biophotonics·Zhendong GuoSung-Liang Chen
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Aug 31, 2019·Journal of Biophotonics·Benjamin LengenfelderFlorian Klämpfl
Sep 17, 2020·Journal of Biophotonics·Heng GuoLei Xi
Oct 29, 2015·Journal of Biomedical Optics·Ye ChenJonathan T C Liu
Nov 16, 2017·Optics Letters·Heng GuoLei Xi
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Nov 2, 2019·Optics Letters·Ajay DangiSri-Rajasekhar Kothapalli
May 16, 2020·Light, Science & Applications·Dengfeng LiYajing Shen
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May 12, 2021·Light, Science & Applications·Dengfeng LiYajing Shen

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