Optimal arterial phase imaging for detection of hypervascular hepatocellular carcinoma determined by continuous image capture on 16-MDCT

AJR. American Journal of Roentgenology
Xiaozhou MaDushyant V Sahani

Abstract

The purpose of this study is to estimate the optimal time delay before the initiation of arterial phase scanning for detection of hypervascular hepatocellular carcinoma (HCC) on 16-MDCT when a rapid bolus injection of contrast medium is administered. In this prospective study, 25 patients (19 men and six women; mean age, 63.5 years; age range, 50-81 years) with pathologically confirmed HCC were included. Dynamic 16-MDCT imaging was performed in cine mode using 70 mL of nonionic iodinated contrast medium (300 mg I/mL) at an injection rate of 7 mL/s. Four consecutive 5-mm-thick slices at the maximum diameter of the HCC were selected as the region of interest. Time-attenuation curves were generated by region of interest drawn on the aorta, tumor, and liver. Qualitative assessments of conspicuity for contrast medium wash-in, peak, and wash-out of aorta and tumor were performed. There were 108 arterial phase enhancing lesions (mean [+/-SD], 4.9 +/- 2.4 cm; range, 0.7-12.9 cm) in the 25 patients. The maximum Hounsfield value of aorta, tumor, and background liver parenchyma were 463.8 +/- 98 HU, 106.5 +/- 19 HU, and 98.3 +/- 14 HU, respectively. At the time of onset of peak tumor enhancement, the difference between tumor density and b...Continue Reading

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Citations

Apr 16, 2010·European Radiology·Long-Jiang ZhangGuang-Ming Lu
Feb 9, 2013·Wiener medizinische Wochenschrift·Benjamin HenningerWerner Jaschke
Jun 23, 2009·Lab Animal·Jens PinkernelleUlf K M Teichgräber
Sep 18, 2013·European Journal of Radiology·Nicole WinklerAkram Shaaban
May 25, 2020·Seminars in Ultrasound, CT, and MR·Abdullah O AleneziAnia Z Kielar

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