Optimal brain perfusion CT coverage in patients with acute middle cerebral artery stroke.

AJNR. American Journal of Neuroradiology
A D FurtadoMax Wintermark

Abstract

PCT has emerged as an alternative to MR imaging for the assessment of patients with suspected acute stroke. However, 1 disadvantage of PCT is its limited anatomic coverage, which may impact the characterization of hemispheric ischemic strokes. The purpose of this study was to determine the optimal brain CT coverage required to accurately estimate the size of the infarct core relative to the MCA territory and the infarct-penumbra mismatch, by using a criterion standard of these parameters measured on PCT with 80-mm z-axis coverage. Fifty-one patients with acute ischemic hemispheric stroke underwent PCT scanning (2 boluses, total coverage of 80 mm, 16 x 5 mm sections) within the first 24 hours of symptom onset and a follow-up NCCT of the brain between 3 days and 3 months after the initial stroke CT study. The volumes of PCT infarct and penumbra for each possible extent of z-axis coverage derived from the individual PCT sections were recorded (beginning with 5 mm of z-axis coverage above the orbits and then increasing the coverage in 5-mm increments in the z-axis up to 80 mm above the orbits). The infarct-penumbra mismatch and the size of the infarction relative to the MCA territory were calculated for each extent of z-axis covera...Continue Reading

References

Apr 1, 1976·The British Journal of Radiology·E ZilkhaJ Marshall
Apr 25, 2003·The British Journal of Radiology·K A Miles, M R Griffiths
Aug 10, 2004·Neuroradiology·J M Esteban, V Cervera
May 26, 2005·Stroke; a Journal of Cerebral Circulation·K S ButcherUNKNOWN EPITHET Investigators
Oct 18, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·P A BarberUNKNOWN ASPECTS Study Group
Apr 1, 2006·Stroke; a Journal of Cerebral Circulation·Anthony J FurlanUNKNOWN DEDAS Investigators
Aug 4, 2007·Stroke; a Journal of Cerebral Circulation·Keith W MuirShelagh B Coutts
Sep 22, 2007·AJNR. American Journal of Neuroradiology·M Luby, S Warach
Jan 10, 2008·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Wataru KakudaUNKNOWN DEFUSE Investigators
Mar 8, 2008·The Journal of Emergency Medicine·Ansaar T RaiJack E Riggs

❮ Previous
Next ❯

Citations

Dec 29, 2013·AJNR. American Journal of Neuroradiology·W F ChuW Y Guo
Jul 12, 2014·Annual Review of Biomedical Engineering·Daniel Thomas Ginat, Rajiv Gupta
Sep 18, 2014·Neuroradiology·B J EmmerM A A van Walderveen
Jun 1, 2012·Translational Stroke Research·Guangming ZhuMax Wintermark
Apr 3, 2012·Techniques in Vascular and Interventional Radiology·Michael C HurleySameer Ansari
Oct 12, 2012·Insights Into Imaging·Josef VymazalLadislava Janouskova
Sep 17, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Lorenz BreuerTobias Engelhorn
Mar 4, 2015·Current Treatment Options in Cardiovascular Medicine·William A Copen
Aug 24, 2016·The British Journal of Radiology·Arkadiusz SzarmachPawel J Winklewski
May 19, 2017·Topics in Magnetic Resonance Imaging : TMRI·Pradeep KrishnanRichard I Aviv
Jan 17, 2012·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Young Wook JeonUNKNOWN Brain Research Group

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.