Optimal initiation of Helicobacter pylori eradication in patients with peptic ulcer bleeding

World Journal of Gastroenterology : WJG
Hyuk YoonN Kim

Abstract

To evaluate when Helicobacter pylori (H. pylori) eradication therapy (ET) should be started in patients with peptic ulcer bleeding (PUB). Clinical data concerning adults hospitalized with PUB were retrospectively collected and analyzed. Age, sex, type and stage of peptic ulcer, whether endoscopic therapy was performed or not, methods of H. pylori detection, duration of hospitalization, and specialty of the attending physician were investigated. Factors influencing the confirmation of H. pylori infection prior to discharge were determined using multiple logistic regression analysis. The H. pylori eradication rates of patients who received ET during hospitalization and those who commenced ET as outpatients were compared. A total of 232 patients with PUB were evaluated for H. pylori infection by histology and/or rapid urease testing. Of these patients, 53.7% (127/232) had confirmed results of H. pylori infection prior to discharge. In multivariate analysis, duration of hospitalization and ulcer stage were factors independently influencing whether H. pylori infection was confirmed before or after discharge. Among the patients discharged before confirmation of H. pylori infection, 13.3% (14/105) were lost to follow-up. Among the pat...Continue Reading

References

Feb 16, 2005·Alimentary Pharmacology & Therapeutics·M J R JanssenJ B M J Jansen
Feb 24, 2006·The American Journal of Gastroenterology·Javier P Gisbert, Víctor Abraira
Jun 6, 2009·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Emili GenéRafel Azagra
Nov 26, 2009·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Il Kwun ChungUNKNOWN Korean Association of Gastroenterology
Apr 8, 2011·Gut·Joseph J Y SungUNKNOWN Asia-Pacific Working Group
Aug 9, 2011·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Joshua GreenspoonUNKNOWN International Consensus Upper Gastrointestinal Bleeding Conference Group
Feb 9, 2012·The American Journal of Gastroenterology·Loren Laine, Dennis M Jensen
Apr 12, 2012·Gut·Peter MalfertheinerUNKNOWN European Helicobacter Study Group
May 24, 2012·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Jin Joo KimIn Sung Song
Feb 8, 2013·Journal of Clinical Gastroenterology·Nimish Vakil, Dino Vaira
Jun 12, 2013·Lancet·James Y W LauFrancis K L Chan
Aug 21, 2013·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Sang Gyun KimUNKNOWN Korean College of Helicobacter and Upper Gastrointestinal Research

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Citations

Jan 11, 2020·World Journal of Emergency Surgery : WJES·Antonio TarasconiFausto Catena
Apr 10, 2020·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Shria KumarDavid S Goldberg

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