Optimal management of septic shock. Rapid recognition and institution of therapy are crucial

Postgraduate Medicine
Stephen J Fitch, James R Gossage

Abstract

Septic shock is a common problem in hospitalized patients. Optimal management depends on rapid recognition, aggressive restoration of circulating volume with fluid boluses, initiation of appropriate antibiotic therapy, implementation of adequate monitoring, and meticulous attention to the details of care. Mean arterial pressure should be increased to between 65 and 75 mm Hg as soon as possible to reduce the likelihood of multiorgan dysfunction. Despite these therapeutic maneuvers, however, mortality rates are likely to remain high until the development of therapies that better target the underlying mechanisms of sepsis.

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Citations

Dec 21, 2002·Pharmacotherapy·Maria I Rudis, Douglas N Fish
Dec 23, 2011·Journal of Biomedicine & Biotechnology·Xingjun LuoZuojun Lv
Feb 25, 2003·Critical Care Nursing Clinics of North America·Marilyn Sawyer Sommers
Jul 4, 2006·International Journal of Antimicrobial Agents·Mohammad Reza RafatiMohammad Reza Fazeli
Dec 10, 2002·Journal of the Royal Army Medical Corps·R Mackenzie, R C Sutcliffe
Mar 8, 2006·The Canadian Journal of Cardiology·Simona L BarAndrew Ignaszewski

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