Optimal operational conditions for supercontinuum-based ultrahigh-resolution endoscopic OCT imaging

Optics Letters
Wu YuanXingde Li

Abstract

We investigated the optimal operational conditions for utilizing a broadband supercontinuum (SC) source in a portable 800 nm spectral-domain (SD) endoscopic OCT system to enable high resolution, high-sensitivity, and high-speed imaging in vivo. A SC source with a 3-dB bandwidth of ∼246  nm was employed to obtain an axial resolution of ∼2.7  μm (in air) and an optimal detection sensitivity of ∼-107  dB with an imaging speed up to 35 frames/s (at 70 k A-scans/s). The performance of the SC-based SD-OCT endoscopy system was demonstrated by imaging guinea pig esophagus in vivo, achieving image quality comparable to that acquired with a broadband home-built Ti:sapphire laser.

Citations

Sep 17, 2016·Scientific Reports·Janani S IyerKonstantina M Stankovic
Jun 24, 2016·Journal of Biomedical Optics·Yanmei LiangXingde Li
May 12, 2017·Journal of Biomedical Optics·Lian DuanHao F Zhang
Mar 24, 2016·Journal of Biomedical Optics·Xinwen YaoChristine P Hendon
Sep 12, 2020·Molecular Oncology·Yubo TangRebecca Richards-Kortum
May 9, 2019·Biomedical Optics Express·Jia-Pu SyuWen-Chuan Kuo
Jul 1, 2017·Biomedical Optics Express·Jianlin ZhangXingde Li
Jul 9, 2020·Biomedical Optics Express·Cong WangDeyin Li
Jul 1, 2017·Biomedical Optics Express·Michalina J GoraXingde Li
Nov 16, 2017·Optics Letters·Michael MariaAdrian Podoleanu
Jun 30, 2021·Light, Science & Applications·Shreesha Rao D SOle Bang

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