Optimal parameters for clinical implementation of breast cancer patient setup using Varian DTS software.

Journal of Applied Clinical Medical Physics
Sook Kien NgYulia Lyatskaya

Abstract

Digital tomosynthesis (DTS) was evaluated as an alternative to cone-beam computed tomography (CBCT) for patient setup. DTS is preferable when there are constraints with setup time, gantry-couch clearance, and imaging dose using CBCT. This study characterizes DTS data acquisition and registration parameters for the setup of breast cancer patients using nonclinical Varian DTS software. DTS images were reconstructed from CBCT projections acquired on phantoms and patients with surgical clips in the target volume. A shift-and-add algorithm was used for DTS volume reconstructions, while automated cross-correlation matches were performed within Varian DTS software. Triangulation on two short DTS arcs separated by various angular spread was done to improve 3D registration accuracy. Software performance was evaluated on two phantoms and ten breast cancer patients using the registration result as an accuracy measure; investigated parameters included arc lengths, arc orientations, angular separation between two arcs, reconstruction slice spacing, and number of arcs. The shifts determined from DTS-to-CT registration were compared to the shifts based on CBCT-to-CT registration. The difference between these shifts was used to evaluate the so...Continue Reading

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Citations

Sep 7, 2013·Medical Physics·John R van Sörnsen de KosteWilko F A R Verbakel
Apr 14, 2016·Journal of Applied Clinical Medical Physics·Hui Yan, Jian-Rong Dai

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Methods Mentioned

BETA
imaging technique

Software Mentioned

Varian
Varian DTS
DTS
Varian OBI
Offline Review

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