PMID: 11910728Mar 26, 2002Paper

Optimal peep in ARDS. Changing concepts and current controversies

Critical Care Clinics
Mitchell M Levy

Abstract

From many recently performed studies, it is clear that a criterion standard for determining the optimal positive end-expiratory pressure (PEEP) level in patients with acquired respiratory distress syndrome (ARDS) does not exist. What is evident and consistent, however, are several points such the optimal PEEP level ultimately represents a balance between regional areas of overstretching and regional derecruitment; higher levels of PEEP may be required early in ARDS, independent of oxygenation requirements; and the exact method for titrating PEEP in patients with ARDS remains to be determined. These points and others are delineated and discussed in this article.

References

Feb 6, 1975·The New England Journal of Medicine·P M SuterM D Isenberg
Jan 1, 1992·Intensive Care Medicine·B Lachmann
Aug 1, 1990·The American Review of Respiratory Disease·T C CorbridgeJ I Sznajder
Sep 1, 1987·The American Review of Respiratory Disease·L GattinoniM Bombino
Oct 1, 1987·British Journal of Anaesthesia·E P ArgirasM K Sykes
Apr 1, 1973·Respiration Physiology·D H GlaisterJ Milic-Emili
Aug 1, 1995·American Journal of Respiratory and Critical Care Medicine·F BrunetJ F Dhainaut
Jun 1, 1995·American Journal of Respiratory and Critical Care Medicine·L GattinoniF Valenza
May 1, 1994·American Journal of Respiratory and Critical Care Medicine·J G MuscedereA S Slutsky
Apr 28, 1993·JAMA : the Journal of the American Medical Association·L GattinoniR Fumagalli
Mar 1, 1997·The Journal of Clinical Investigation·L TremblayA S Slutsky
Feb 5, 1998·The New England Journal of Medicine·M B AmatoC R Carvalho
Jul 9, 1998·American Journal of Respiratory and Critical Care Medicine·K G Hickling
Jan 5, 1999·American Journal of Respiratory and Critical Care Medicine·Q LuJ J Rouby
Apr 8, 1999·American Journal of Respiratory and Critical Care Medicine·B JonsonL Brochard
Jul 3, 1999·American Journal of Respiratory and Critical Care Medicine·M A MartynowiczR D Hubmayr
Feb 15, 2000·American Journal of Respiratory and Critical Care Medicine·R S HarrisJ G Venegas
May 4, 2000·The New England Journal of Medicine·UNKNOWN Acute Respiratory Distress Syndrome NetworkArthur Wheeler
Dec 9, 2000·American Journal of Respiratory and Critical Care Medicine·M Lichtwarck-AschoffU H Sjöstrand
Nov 1, 1963·Anesthesiology·N C STAUB

❮ Previous
Next ❯

Citations

Apr 25, 2006·Critical Care Medicine·David N Hager, Roy G Brower
Jan 27, 2007·Critical Care Medicine·Carissa L Bellardine BlackKenneth R Lutchen
Nov 27, 2010·Biomedical Engineering Online·Ashwath SundaresanGeoffrey M Shaw

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The New England Journal of Medicine
R G BrowerNational Heart, Lung, and Blood Institute ARDS Clinical Trials Network
The New England Journal of Medicine
Mitchell M Levy
Critical Care : the Official Journal of the Critical Care Forum
L Brochard
© 2022 Meta ULC. All rights reserved