Optimal region-of-interest settings for tissue characterization based on ultrasonic elasticity imaging

Ultrasound in Medicine & Biology
Kentaro TsuzukiHiroshi Kanai

Abstract

Pathologic changes in arterial walls significantly influence their mechanical properties. We have developed a correlation-based method, the phased tracking method, for measurement of the regional elasticity of the arterial wall. Using this method, elasticity distributions of lipids, blood clots, fibrous tissue and calcified tissue were measured by in-vitro experiments of excised arteries (mean +/- SD: lipids, 89 +/- 47 kPa; blood clots, 131 +/- 56 kPa; fibrous tissue, 1022 +/- 1040 kPa; calcified tissue, 2267 +/- 1228 kPa). It was found that arterial tissues can be classified into soft tissues (lipids and blood clots) and hard tissues (fibrous tissue and calcified tissue) on the basis of their elasticity. However, there are large overlaps between elasticity distributions of lipids and blood clots and those of fibrous tissue and calcified tissue. Thus, it was difficult to differentiate lipids from blood clots and fibrous tissue from calcified tissue by setting a threshold for a single elasticity value. Therefore, we previously proposed a tissue classification method using the elasticity distribution in each small region. In this method, the elasticity distribution of each small region of interest (ROI) (not a single pixel) in an...Continue Reading

References

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Citations

Apr 1, 2013·Journal of Medical Ultrasonics·Hideyuki HasegawaHiroshi Kanai
Jan 9, 2020·Computer Methods in Biomechanics and Biomedical Engineering·Kesong XuHaiyan Lu

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