Optimal representation of sensory information by neural populations

Nature Neuroscience
Mehrdad Jazayeri, J Anthony Movshon

Abstract

Sensory information is encoded by populations of neurons. The responses of individual neurons are inherently noisy, so the brain must interpret this information as reliably as possible. In most situations, the optimal strategy for decoding the population signal is to compute the likelihoods of the stimuli that are consistent with an observed neural response. But it has not been clear how the brain can directly compute likelihoods. Here we present a simple and biologically plausible model that can realize the likelihood function by computing a weighted sum of sensory neuron responses. The model provides the basis for an optimal decoding of sensory information. It explains a variety of psychophysical observations on detection, discrimination and identification, and it also directly predicts the relative contributions that different sensory neurons make to perceptual judgments.

References

Oct 7, 1977·Science·R Sekuler, K Ball
Feb 1, 1985·Journal of the Optical Society of America. A, Optics and Image Science·D Regan, K I Beverley
Feb 1, 1985·Journal of the Optical Society of America. A, Optics and Image Science·E H Adelson, J R Bergen
Apr 8, 1994·Science·C D Salzman, W T Newsome
Nov 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·H S Seung, H Sompolinsky
Nov 1, 1993·Visual Neuroscience·K H BrittenJ A Movshon
Jun 1, 1994·Journal of Computational Neuroscience·E Salinas, L F Abbott
Mar 13, 1997·Nature·L H SnyderR A Andersen
May 30, 1998·Vision Research·E P Simoncelli, D J Heeger
Aug 15, 1998·Journal of Neurophysiology·K H Britten, W T Newsome
Jul 21, 1999·Nature Neuroscience·S DeneveA Pouget
Feb 13, 2001·Trends in Cognitive Sciences·J I. Gold, M N. Shadlen
Oct 16, 2001·Journal of Neurophysiology·M N Shadlen, W T Newsome
May 22, 2002·Nature Neuroscience·Yair WeissEdward H Adelson
Jul 23, 2002·Nature Neuroscience·Alexei A KoulakovJohn E Lisman
Apr 22, 2003·Annual Review of Neuroscience·Alexandre PougetRichard S Zemel
Oct 25, 2003·Cerebral Cortex·Mark E MazurekMichael N Shadlen
Mar 24, 2004·Trends in Neurosciences·Philip L Smith, Roger Ratcliff
May 8, 2004·Neural Computation·Maoz Shamir, Haim Sompolinsky
Dec 21, 2004·Nature Neuroscience·Gopathy Purushothaman, David C Bradley
Apr 9, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Adam Kohn, Matthew A Smith

❮ Previous
Next ❯

Citations

May 28, 2013·Experimental Brain Research·Nadejda BochevaMiroslava Stefanova
Apr 1, 2008·Biological cybernetics·Tzvetomir Tzvetanov, Thilo Womelsdorf
Mar 20, 2010·Biological cybernetics·William H Nesse, Gregory A Clark
Oct 6, 2007·Journal of Computational Neuroscience·Heesoo Kim, Shaowen Bao
May 25, 2010·Bulletin of Mathematical Biology·G PfuhlR Biegler
Sep 5, 2009·Cognitive Neurodynamics·Jerome Feldman
Mar 8, 2013·Behavioural Processes·Maik C StüttgenFrank Jäkel
Jan 31, 2014·Visual Neuroscience·J Anthony Movshon
Apr 6, 2007·Nature·Mehrdad Jazayeri, J Anthony Movshon
Jan 23, 2009·Nature Neuroscience·Maik C Stüttgen, Cornelius Schwarz
Nov 9, 2010·Nature Neuroscience·Katrin HerrmannDavid J Heeger
Jan 11, 2011·Nature Neuroscience·Arnulf B A GrafJ Anthony Movshon
Jun 7, 2011·Nature Neuroscience·Ahna R GirshickEero P Simoncelli
Nov 22, 2011·Nature Neuroscience·Christopher R FetschDora E Angelaki
Oct 2, 2012·Nature Neuroscience·Claudio SimonciniGuillaume S Masson
Nov 28, 2012·Nature Neuroscience·Sheng LiuDora E Angelaki
Aug 21, 2013·Nature Neuroscience·Alexandre PougetPeter E Latham
Oct 27, 2006·Nature Neuroscience·Emilio Salinas
Oct 24, 2006·Nature Neuroscience·Wei Ji MaAlexandre Pouget
Aug 14, 2008·Proceedings of the National Academy of Sciences of the United States of America·Andrew E WelchmanHeinrich H Bülthoff
Mar 27, 2009·Proceedings of the National Academy of Sciences of the United States of America·Lee M Miller, Gregg H Recanzone
May 5, 2010·Proceedings of the National Academy of Sciences of the United States of America·Marios G PhiliastidesHauke R Heekeren
Mar 31, 2012·Proceedings of the National Academy of Sciences of the United States of America·Katharina Merten, Andreas Nieder
Mar 28, 2009·Proceedings. Biological Sciences·J V StoneJ Porrill
Oct 22, 2010·Proceedings. Biological Sciences·Neil W RoachPaul V McGraw
Aug 13, 2011·Proceedings. Biological Sciences·James HeronDavid Whitaker
Jul 16, 2010·Journal of Neurophysiology·Miranda Scolari, John T Serences
May 21, 2010·Journal of Neurophysiology·Sameer Saproo, John T Serences
Feb 5, 2010·Journal of Neurophysiology·Tao Zhang, Kenneth H Britten
Apr 23, 2010·Journal of Neurophysiology·John T Serences, Sameer Saproo
Apr 2, 2010·Journal of Neurophysiology·David M Schneider, Sarah M N Woolley
Aug 19, 2009·Neural Computation·Shai Litvak, Shimon Ullman
Dec 24, 2009·Neural Computation·Jiaxiang Zhang, Rafal Bogacz
Aug 19, 2009·Neural Computation·Peggy SerièsEero P Simoncelli
Aug 28, 2012·Neural Computation·Nathan F Lepora, Kevin N Gurney
Mar 23, 2013·Neural Computation·Stefan HabenschussWolfgang Maass
Nov 1, 2008·PLoS Computational Biology·Carina Curto, Vladimir Itskov
Jul 27, 2010·PLoS Computational Biology·Jonathan B DingwellJoseph P Cusumano
Mar 8, 2011·PLoS Computational Biology·Martin Boerlin, Sophie Denève
Apr 19, 2012·PLoS Computational Biology·Tom PutzeysRobbe Goris
Jul 13, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·John G O'Leary, Stephen G Lisberger
Jun 8, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Tiffany HoJohn T Serences

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
H S Seung, H Sompolinsky
Trends in Cognitive Sciences
Joshua I Gold, Michael N Shadlen
Journal of the Optical Society of America. A, Optics and Image Science
D Regan, K I Beverley
© 2022 Meta ULC. All rights reserved