PMID: 11934023Apr 6, 2002Paper

Optimal temperature input design for estimation of the square root model parameters: parameter accuracy and model validity restrictions

International Journal of Food Microbiology
K BernaertsJ F M Van Impe

Abstract

As part of the model building process, parameter estimation is of great importance in view of accurate prediction making. Confidence limits on the predicted model output are largely determined by the parameter estimation accuracy that is reflected by its parameter estimation covariance matrix. In view of the accurate estimation of the Square Root model parameters, Bernaerts et al. have successfully applied the techniques of optimal experiment design for parameter estimation [Int. J. Food Microbiol. 54 (1-2) (2000) 27]. Simulation-based results have proved that dynamic (i.e., time-varying) temperature conditions characterised by a large abrupt temperature increase yield highly informative cell density data enabling precise estimation of the Square Root model parameters. In this study, it is shown by bioreactor experiments with detailed and precise sampling that extreme temperature shifts disturb the exponential growth of Escherichia coli K12. A too large shift results in an intermediate lag phase. Because common growth models lack the ability to model this intermediate lag phase, temperature conditions should be designed such that exponential growth persist even though the temperature may be changing. The current publication pre...Continue Reading

References

Nov 1, 1994·International Journal of Food Microbiology·J Baranyi, T A Roberts
Sep 1, 1995·International Journal of Food Microbiology·J BaranyiB M Mackey
Nov 24, 1999·International Journal of Food Microbiology·K J VersyckJ F Van Impe

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Citations

May 12, 2004·International Journal of Food Microbiology·P R ShortenT K Soboleva
Feb 2, 2010·Psychometrika·Joris Mulder, Wim J van der Linden
Jul 20, 2012·International Journal of Food Microbiology·E Van Derlinden, J F Van Impe
Oct 7, 2008·International Journal of Food Microbiology·E Van DerlindenJ F Van Impe
May 10, 2005·International Journal of Food Microbiology·Koen Grijspeerdt, Koen De Reu
Jul 19, 2016·International Journal of Food Microbiology·Daniel Angelo LonghiJoão Borges Laurindo
Apr 28, 2005·International Journal of Food Microbiology·K BernaertsJ F Van Impe
Sep 30, 2004·Journal of Food Protection·Kristel BernaertsJan F Van Impe
Jun 1, 2021·Journal of Food Science·Maria C GiannakourouNikolaos G Stoforos

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