Optimisation and comparison of several microextraction/methylation methods for determining haloacetic acids in water using gas chromatography

Analytical and Bioanalytical Chemistry
M J Cardador, M Gallego

Abstract

This article presents the different modes and configurations of liquid-phase microextraction (LPME) through comparison with headspace solid-phase microextraction (HS-SPME) for the simultaneous extraction/methylation of the nine haloacetic acids (HAAs) found in water. This is the first analytical case reported of solvent bar extraction-preconcentration-derivatisation assisted by an ion-pairing transfer for HAAs. In this method, 5 muL of the organic extractant, decane, was confined within a hollow-fibre membrane that was placed in a stirred aqueous sample containing the derivatising reagents (dimethylsulphate with a tetrabutylammonium salt). With heating at 45 degrees C in the HS-SPME method, some organic solvents (extractant, excess of derivatising reagent) are also volatilised and compete with the esters on the fibre (the fibre is damaged and it can be reused only 50-60 times). In addition, the HS-SPME method provides inadequate sensitivity (limits of detections between 0.3 and 5 microg/L) to quantify HAAs at the level usually found in drinking waters. Alternative headspace LPME methods for HAAs require heating (45 degrees C, 25 min) to derivatise and volatilise the esters but, by using solvent bar microextraction (SBME), the e...Continue Reading

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Citations

Dec 17, 2014·Environment International·Tiffany L L TeoStuart J Khan
Jan 17, 2012·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Christopher S A SáIsabel B Pereira
Apr 15, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Alshymaa A Aly, Tadeusz Górecki
Dec 13, 2018·Journal of Water and Health·Huma IlyasJan Peter van der Hoek

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