Optimisation of high-pressure ultrasonic-assisted extraction and antioxidant capacity of polysaccharides from the rhizome of Ligusticum chuanxiong

International Journal of Biological Macromolecules
Jin-Liang LiuFan-Lei Kong

Abstract

High-pressure ultrasound-assisted extraction was used to extract polysaccharides from the Ligusticum chuanxiong rhizomes. Three independent variables, namely, extraction temperature (X1), ultrasonic power (X2) and extraction time (X3) were investigated. Response surface methodology was performed based on the results of single-factor tests. Experimental data were fitted to a second-order polynomial equation using multiple regression analysis, and results were examined using appropriate statistical methods. The optimal conditions were as follows: extraction temperature of 85°C, ultrasonic power of 187 W and extraction time of 29 min. Under these conditions, the experimental yield of polysaccharides was 5.33%, which is close to the predicted yield of 5.41%. The extracted and purified polysaccharides showed excellent antioxidative effects on 2,2-diphenyl-1-picryl-hydrazy, hydroxyl and superoxide radicals in vitro.

References

Feb 13, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jin-Liang LiuFan-Lei Kong

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Citations

Jan 26, 2016·International Journal of Biological Macromolecules·Hongmin DongWen Qin
Nov 28, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Xuejing JiaChengwei He
Dec 30, 2015·International Journal of Biological Macromolecules·Jie HuMeiwan Chen
Mar 31, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Fengwei LiTao Shao
May 24, 2016·International Journal of Molecular Sciences·Xueping Song, Jun Tang
Nov 5, 2016·International Journal of Biological Macromolecules·Zhenyu ChengYu Feng
Oct 31, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Aleksandra ShedoevaChen Fan
Jun 20, 2020·Environmental Science and Pollution Research International·Mohammad Beiranvand, Alireza Ghiasvand
Feb 22, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yuan-Feng ZouBerit Smestad Paulsen
Apr 10, 2019·Polymers·Salima T MinzanovaVasili A Milyukov
Nov 3, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Jinhui ShiHongmei Zhang

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