PMID: 2502250May 20, 1989Paper

Optimisation of positive and expiratory pressure for maximal delivery of oxygen to tissues using oesophageal Doppler ultrasonography

BMJ : British Medical Journal
M Singer, D Bennett

Abstract

To assess oesophageal Doppler ultrasonography as a convenient means of optimising positive end expiratory pressure for maximal delivery of oxygen to tissues. Measurements of blood flow, arterial oxygen saturation, and cardiac output by thermodilution (when available) at baseline and at 20-30 minutes after each incremental increase (2.5-5.0 cm H2O) in positive and expiratory pressure to a maximum of 20.0 cm H2O. If the cardiac output fell by more than 15% measurements were repeated after stepwise decreases in positive end expiratory pressure. No other manoeuvre such as endotracheal suction or changing ventilator settings, drug or fluid dosage, or the patient's position was performed for at least one hour before the start of the study or during it. Intensive care unit. 10 Patients being mechanically ventilated for acute respiratory failure who had stable haemodynamic and blood gas values and required a fractional inspired oxygen concentration of greater than or equal to 0.45. They were assessed on a total of 11 occasions. Incremental increases in positive end expiratory pressure followed when indicated by stepwise decreases. The positive end expiratory pressure providing maximal delivery of oxygen to tissues. Arterial oxygen satu...Continue Reading

References

Feb 6, 1975·The New England Journal of Medicine·P M SuterM D Isenberg
Mar 1, 1987·British Heart Journal·A D HainsE B Raftery
Jun 1, 1985·British Heart Journal·M J O'HaraE B Raftery
Apr 25, 1974·The New England Journal of Medicine·G A FooteM Hodges
Dec 1, 1984·British Heart Journal·P J LowryW A Littler
Dec 1, 1982·Critical Care Medicine·L D NelsonD R Westenskow
Feb 1, 1980·Critical Care Medicine·M Walkinshaw, W C Shoemaker
Feb 12, 1981·The New England Journal of Medicine·F JardinJ P Bourdarias
Jun 1, 1982·Critical Care Medicine·M P Grace, D M Greenbaum
Jan 1, 1981·Circulation Research·A M Katz, F C Messineo

❮ Previous
Next ❯

Citations

Sep 28, 2001·British Journal of Anaesthesia·H A Leather, P F Wouters
May 1, 1993·Postgraduate Medical Journal·S Sinclair, M Singer
Jul 18, 2009·Anesthesia and Analgesia·Patrick SchoberLothar A Schwarte
Oct 21, 2009·Journal of Clinical Monitoring and Computing·Patrick SchoberLothar A Schwarte
Mar 12, 2015·The British Journal of Surgery·J C Gómez-IzquierdoG Baldini

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.