Optimising TNM Staging of Patients with Prostate Cancer Using WB-MRI

Journal of the Belgian Society of Radiology
Vassiliki PasoglouFrederic E Lecouvet

Abstract

Multiparametric Magnetic Resonance Imaging (mp-MRI) is the current standard of reference for the local staging of prostate cancer (PCa). On the other hand, despite the low sensitivity and specificity of Technetium Bone Scanning (BS) for the detection of bone metastases (BM) and of Body Computed Tomography CT for the detection of lymph node metastases (LNM), these techniques are routinely used, in the current clinical practice. Nevertheless, whole Body MRI (WB-MRI) and Positron Emission Tomography Computed Tomography (PET-CT) are emerging as robust tools for the staging of oncologic patients, including those with (PCa). The available techniques (BS, WB-MRI, PET, CT) for the detection of BM in oncologic patients were compared and showed striking center differences in terms of anatomic sequences and planes used. This heterogeneity and the long acquisition time of WB-MRI protocols - due to the addition of multiple anatomic sequences in different planes - questioned whether a single three dimensional (3D) sequence could replace the multiple anatomic sequences used for node and bone staging of PCa. We demonstrated that WB-MRI is a credible tool for the detection of bone and node metastasis. The second question addressed the possibili...Continue Reading

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Citations

Feb 27, 2017·Journal of the Belgian Society of Radiology·Piet Vanhoenacker

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Methods Mentioned

BETA
biopsies
imaging techniques
X-Rays

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