Optimization of contrast timing for breath-hold three-dimensional MR angiography

Journal of Magnetic Resonance Imaging : JMRI
T F HanyJ F Debatin

Abstract

The purpose of this study was to determine the influence of various factors (age, weight, breathing, saline flush) on the contrast kinetics of a test bolus injection for the purpose of calculating the scan delay for optimized contrast-enhanced three-dimensional MR angiography. Initially, the test bolus administration was optimized by evaluating the influence of breathing (breathing versus breath-hold) and the administration of a saline flush after the contrast injection (no flush versus flush) on the kinetics of a 4-ml Gd-DTPA test bolus injection in three healthy volunteers. Subsequently, in 33 patients referred for three-dimensional MR angiography of the renal arteries, test bolus kinetics were correlated to age, weight, and heart rate. In addition, the image quality of the three-dimensional MR angiograms was assessed on a four-point scale with regard to vessel visibility. The administration of a saline flush after the contrast injection significantly shortened the first appearance time (14 versus 16 seconds, P < .05), as well as the time to maximal signal intensity (SI) (6 versus 10 seconds, P < .05) and increased both maximum (67 versus 151 seconds, P < .05) and the SI slope (6.4 versus 20.5 seconds, P < .05). Breath-holdin...Continue Reading

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Citations

Oct 3, 1999·Journal of Magnetic Resonance Imaging : JMRI·M R PrinceJ M Rubin
Nov 5, 1999·Journal of Magnetic Resonance Imaging : JMRI·M A NeimatallahM R Prince
Dec 3, 1999·Journal of Magnetic Resonance Imaging : JMRI·J SvenssonL E Olsson
Dec 3, 1999·Journal of Magnetic Resonance Imaging : JMRI·S S HalliburtonJ D Rothpletz
Feb 17, 2000·Journal of Magnetic Resonance Imaging : JMRI·T M Grist
Apr 15, 2000·Journal of Magnetic Resonance Imaging : JMRI·S G RuehmJ F Debatin
Nov 26, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S B FainJ Huston
Feb 19, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·K K VigenC A Mistretta
Sep 19, 2000·Journal of Magnetic Resonance Imaging : JMRI·R FrayneC A Mistretta
Oct 26, 2000·Journal of Magnetic Resonance Imaging : JMRI·J M CzumP L Choyke
Sep 5, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Andrew V BargerCharles A Mistretta
Jul 11, 1998·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·A H WilmanJ P Debbins
Nov 3, 2009·European Radiology·Akihiro TanimotoLuigi Grazioli
Jun 7, 2005·Magnetic Resonance Imaging Clinics of North America·Kambiz NaelJ Paul Finn
Jun 6, 2006·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Hasan K Kabul, Klaus D Hagspiel
Mar 13, 2003·Radiologic Clinics of North America·Florian M VogtJörg F Debatin
Apr 5, 2001·European Journal of Radiology·H BosmansG Marchal
Oct 12, 2001·Magnetic Resonance Imaging·J T HeverhagenH J Wagner
May 21, 2003·Academic Radiology·Giacomo LuccichentiPaolo Pavone
Oct 10, 1998·Investigative Radiology·D LiE M Haacke
Nov 26, 2002·Investigative Radiology·M V KnoppH R Hentrich
Aug 28, 1999·Radiographics : a Review Publication of the Radiological Society of North America, Inc·A OkumuraY Dodo
Nov 11, 1999·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Q DongM R Prince
Feb 22, 2000·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Y WatanabeY Dodo

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