Optimization of Geriatric Pharmacotherapy: Role of Multifaceted Cooperation in the Hospital Setting

Drugs & Aging
Mirko PetrovicGraziano Onder

Abstract

Because older patients are more vulnerable to adverse drug-related events, there is a need to ensure appropriate pharmacotherapy in these patients. This narrative review describes approaches to improve pharmacotherapy in older people in the hospital setting. Screening to identify older patients at risk of drug-related problems and adverse drug reactions (ADRs) is the first critical step within a multistep approach to geriatric pharmacotherapy. Two methods that have been developed are the GerontoNet ADR risk score and the Brighton Adverse Drug Reactions Risk (BADRI) model, which take into account a number of factors, the most important of which is the number of medicines. In order to reduce potentially inappropriate prescribing in older patients, different types of interventions exist, such as pharmacist-led medication reviews, educational interventions, computerized decision support systems, and comprehensive geriatric assessment. The effects of these interventions have been studied, sometimes in a multifaceted approach, by combining different techniques. None of the existing interventions shows a clear beneficial effect on patients' health outcomes if applied in isolation; however, when these interventions are combined within ...Continue Reading

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Jan 31, 2019·Ciência & saúde coletiva·Ronara Camila de Souza Groia VelosoAdriano Max Moreira Reis
Oct 30, 2019·British Journal of Clinical Pharmacology·Mayara da Costa ChambelaRoberto Magalhães Saraiva
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Oct 1, 2021·European Geriatric Medicine·E Delgado-Silveira, T Bermejo-Vicedo
Jan 19, 2022·European Journal of Clinical Pharmacology·Nazanin FalconerNeil Cottrell

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