PMID: 8939627Oct 1, 1996Paper

Optimization of heterologous protein production in Escherichia coli

Current Opinion in Biotechnology
M J WeickertP O Olins

Abstract

Escherichia coli has long been the primary prokaryotic host for the synthesis of heterologous proteins. Recent advances have been made in the expression of complex proteins as soluble, functional molecules, complete with prosthetic groups, disulfide bonds, and quaternary structure. The development of alternative promoter and induction strategies has improved the options available for manipulating the expression conditions, which are frequently critical to soluble yield.

References

Nov 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·C W FisherR W Estabrook
Aug 29, 1995·Proceedings of the National Academy of Sciences of the United States of America·L J RomanB S Masters
Oct 10, 1995·Proceedings of the National Academy of Sciences of the United States of America·C GuilhotJ Beckwith
Oct 1, 1995·Current Opinion in Biotechnology·E R LaVallie, J M McCoy
Dec 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·M S ShetR W Estabrook

❮ Previous
Next ❯

Citations

Oct 14, 2004·Applied Microbiology and Biotechnology·F R Schmidt
Jan 22, 2005·Applied Microbiology and Biotechnology·Amardeep KhushooK J Mukherjee
Jan 27, 2006·Applied Microbiology and Biotechnology·Zhinan XuPeilin Cen
Jun 16, 2007·Applied Microbiology and Biotechnology·C Perry Chou
Sep 21, 2007·Applied Microbiology and Biotechnology·Selcuk YildirimChristophe Lacroix
Aug 6, 2008·Applied Biochemistry and Biotechnology·Dasari Venkata Krishna RaoAdibhatla Kali Satya Bhujanga Rao
Jan 13, 2004·Biochemical and Biophysical Research Communications·Jingxing OuAnlong Xu
Jul 27, 2002·Journal of Biotechnology·M M Carrió, A Villaverde
Nov 14, 1997·Current Opinion in Biotechnology·T A Kost
Apr 30, 2003·Journal of Structural Biology·Celia W Goulding, L Jeanne Perry
Mar 26, 2003·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·A UrbanY Motorin
Mar 23, 2006·BMC Biotechnology·Kevin T WattsClaudia Schmidt-Dannert
Jan 5, 2005·Microbial Cell Factories·Hans Peter Sørensen, Kim Kusk Mortensen
Dec 17, 2011·International Journal of Molecular Sciences·Spela Peternel, Radovan Komel
Mar 31, 2011·Future Medicinal Chemistry·Kate MaclaganRenos Savva
Apr 1, 2014·Protein Expression and Purification·Karolina PeciakEmmanuelle Laurine
Sep 12, 2015·Biotechnology Journal·Donghui ChoeByung-Kwan Cho
Mar 31, 2004·Biotechnology and Bioengineering·Nobutaka Nakashima, Tomohiro Tamura
Mar 23, 2010·Protein Expression and Purification·Jawahar SudhamsuBrian R Crane
Jul 15, 2015·Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology·Traci L NessMitch H Weiland
Dec 5, 2014·Extremophiles : Life Under Extreme Conditions·Jonathan MaiangwaThean Chor Leow
Jul 6, 2015·Applied Biochemistry and Biotechnology·Soohyun ParkJinwon Lee
Mar 6, 2015·Bioresource Technology·Sujata Vijay SohoniPramod P Wangikar
Mar 28, 2012·Protein Expression and Purification·Emir Salas SarduyMaría de los A Chavéz Planes
Jan 28, 2015·Protein Expression and Purification·Johannes M PröpsterMario Schubert
Oct 26, 2000·Protein Expression and Purification·S J TangG C Lee
Jul 5, 2016·Protein Expression and Purification·Dhadchayini JeyaharanAnn M Dixon
Mar 21, 2001·Biotechnology & Genetic Engineering Reviews·L M BabéB F Schmidt

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bioinformatics in Biomedicine

Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.