Optimization of Sonotrode Ultrasonic-Assisted Extraction of Proanthocyanidins from Brewers' Spent Grains

Antioxidants
Beatriz Martín-GarcíaMaria Fiorenza Caboni

Abstract

Brewing spent grains (BSGs) are the main by-product from breweries and they are rich of proanthocyanidins, among other phenolic compounds. However, literature on these compounds in BSGs is scarce. Thus, this research focuses on the establishment of ultrasound-assisted extraction of proanthocyanidin compounds in brewing spent grains using a sonotrode. To set the sonotrode extraction up, response surface methodology (RSM) was used to study the effects of three factors, namely, solvent composition, time of extraction, and ultrasound power. Qualitative and quantitative analyses of proanthocyanidin compounds were performed using HPLC coupled to fluorometric and mass spectrometer detectors. The highest content of proanthocyanidins was obtained using 80/20 acetone/water (v/v), 55 min, and 400 W. The established method allows the extraction of 1.01 mg/g dry weight (d.w.) of pronthocyanidins from BSGs; this value is more than two times higher than conventional extraction.

References

Feb 28, 2004·The Journal of Nutrition·Liwei GuRonald L Prior
Mar 16, 2006·Journal of Agricultural and Food Chemistry·Ann Katrin HoltekjølenSvein Halvor Knutsen
May 7, 2008·Cancer Letters·Vijayalakshmi NandakumarSantosh K Katiyar
Jul 19, 2008·Journal of Agricultural and Food Chemistry·Robert MayerGuenther Karl Bonn
May 5, 2009·Journal of Pharmaceutical and Biomedical Analysis·María MonagasRosa Lebrón-Aguilar
Sep 3, 2009·Journal of Agricultural and Food Chemistry·Jarkko K HellströmPirjo H Mattila
Oct 23, 2010·Journal of Agricultural and Food Chemistry·Xinya XuXiaoyi Wei
Jun 13, 2012·Biological & Pharmaceutical Bulletin·Takanori TatsunoTomihisa Ohta
Jun 11, 2014·Critical Reviews in Food Science and Nutrition·Yang Tao, Da-Wen Sun
Aug 24, 2017·Journal of Food Science·Sana IkramMeng Yin
Mar 24, 2018·Antioxidants·Ramiro A CarciochiLeandro Galván D'Alessandro
May 12, 2018·BioMed Research International·Lingyu YangJianqiao Zhong
May 1, 2010·Comprehensive Reviews in Food Science and Food Safety·Mahesh GuptaEimear Gallaghar

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Citations

Dec 11, 2019·Antioxidants·Dimitris P Makris, Selin Şahin
Jul 8, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Joanna HarasymUrszula Kaim
Aug 8, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Beatriz Martín-GarcíaVito Verardo
Sep 3, 2020·Applied Microbiology and Biotechnology·Angela BiancoGiacomo Zara
Nov 25, 2021·Chemical Reviews·Daniela MeroniDaria C Boffito

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