Optimization of thoracic spiral CT: effects of iodinated contrast medium concentration

Radiology
G D RubinP Stark

Abstract

To determine the effect of varying iodine concentration on arterial enhancement and perivenous artifact during thoracic spiral computed tomographic (CT) scanning. One hundred thirty-eight outpatients received 15.0 g (n = 76) or 22.5 g (n = 62) of iodine (300 mg/mL iodine) while undergoing thoracic spiral CT. Patients received either undiluted contrast medium, 1:1 normal saline dilution, or 3:1 normal saline dilution. Contrast medium was injected at a flow rate determined to deliver the entire iodine dose within 40 seconds. Attenuation was measured within arteries and veins. Three blinded thoracic radiologists independently graded perivenous artifact and arterial enhancement. Perivenous artifacts were statistically significantly reduced with successive iodine dilution (P < .002). Arterial enhancement was statistically significantly better with 15.0 g of iodine diluted 1:1 when compared with the same iodine dose undiluted or diluted 3:1 (P < .01). Arterial enhancement achieved with 15.0 g of iodine diluted 1:1 was not statistically significantly lower than that achieved with 22.5 g of iodine diluted 1:1 (P > .31); however, venous artifact was greater with 22.5 g of iodine (P < .004). Reduced iodine concentration appears to dimini...Continue Reading

Citations

Mar 15, 2000·Radiographics : a Review Publication of the Radiological Society of North America, Inc·P BatraJ Goldin
Dec 3, 2003·Radiology·Benjamin M YehMichael B Gotway
Sep 27, 2007·Journal of Computer Assisted Tomography·Su Yeon YouJeung Hee Moon
Mar 27, 2012·Journal of Computer Assisted Tomography·Dawn Renae EngelkemierAfshin Karimi
Oct 8, 1999·Current Problems in Diagnostic Radiology·M B GotwayW R Webb
Jul 25, 2008·European Radiology·Adrian K AndreouAllan Clark
Dec 10, 2009·Radiologic Clinics of North America·Kyongtae T Bae
Mar 1, 2005·Seminars in Roentgenology·James G RavenelU Joseph Schoepf
Oct 25, 2016·Clinical Radiology·W H NijhofM J C M Rutten
Apr 21, 2012·Physics in Medicine and Biology·Fabian EisaWilli A Kalender
Jan 10, 2003·Nihon Hoshasen Gijutsu Gakkai zasshi·Shuji YamamotoShohzoh Nakanishi

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