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Optimized approach for Ion Proton RNA sequencing reveals details of RNA splicing and editing features of the transcriptome

PloS One

May 2, 2017

Roger B BrownScott A Ness

Abstract

RNA-sequencing (RNA-seq) has become the standard method for unbiased analysis of gene expression but also provides access to more complex transcriptome features, including alternative RNA splicing, RNA editing, and even detection of fusion transcripts formed through chromosomal transloc...read more

Mentioned in this Paper

Research
T-Lymphocyte
Proton Therapy
Abnormal Fragmented Structure
CD34
Exons
Sequence Determinations, RNA
TAL1
RNA Isoforms
Transcription, Genetic
4
14
Paper Details
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Optimized approach for Ion Proton RNA sequencing reveals details of RNA splicing and editing features of the transcriptome

PloS One

May 2, 2017

Roger B BrownScott A Ness

PMID: 28459821

DOI: 10.1371/journal.pone.0176675

Abstract

RNA-sequencing (RNA-seq) has become the standard method for unbiased analysis of gene expression but also provides access to more complex transcriptome features, including alternative RNA splicing, RNA editing, and even detection of fusion transcripts formed through chromosomal transloc...read more

Mentioned in this Paper

Research
T-Lymphocyte
Proton Therapy
Abnormal Fragmented Structure
CD34
Exons
Sequence Determinations, RNA
TAL1
RNA Isoforms
Transcription, Genetic
4
14

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RNA Splicing (Keystone)

The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. Discover the latest research on RNA splicing and co-transcriptional splicing in this feed.

Related Papers

PloS One

InFusion: Advancing Discovery of Fusion Genes and Chimeric Transcripts from Deep RNA-Sequencing Data

PloS OneDecember 2, 2016
Konstantin OkonechnikovFernando Garcia-Alcalde
Genome Biology

From RNA-seq reads to differential expression results

Genome BiologyDecember 24, 2010
Alicia OshlackMatthew D Young
Paper Details
References
  • References28
  • Citations
123
  • References28
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
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