Optimized hybrid endoscopic submucosal dissection for colorectal tumors: a randomized controlled trial

Gastrointestinal Endoscopy
Jung Ho BaeJeong-Sik Byeon

Abstract

Colorectal endoscopic submucosal dissection (ESD) is difficult and time consuming. Optimization of ESD with snaring (optimized hybrid ESD) may shorten the procedure time. The purpose of this study was to prospectively compare ESD and optimized hybrid ESD in the colorectum. We prospectively enrolled 70 patients with colorectal neoplasia ≥20 mm. The patients were randomized to receive either ESD (36 patients) or optimized hybrid ESD (34 patients). In the optimized hybrid ESD group, snare resection was performed after an adequate amount of submucosal dissection. The primary outcome was procedure time. Secondary outcomes were en bloc and complete resection rates and adverse event rates. ESD could not be completed in 5 patients (13.9%) in the ESD group because of technical difficulties. We tried hybrid ESD to finish the resection, and en bloc resection was achieved in 4 patients (80%). The mean procedure time was shorter in the optimized hybrid ESD group compared with the ESD group (27.4 vs 40.6 minutes; P = .005). The en bloc resection rates were similar (94.1% vs 100%; P = .493), as were the complete resection rates (91.2% vs 93.5%; P > .999) and perforation rates (3 patients [8.8%] vs 2 patients [6.5%]; P > .999). Optimized hybri...Continue Reading

References

Jun 27, 2007·Gastrointestinal Endoscopy·Shinji TanakaKazuaki Chayama
Oct 2, 2007·Gastrointestinal Endoscopy·Toshio UraokaHiroyuki Okada
Jul 16, 2010·Scandinavian Journal of Gastroenterology·Aki MatsumotoKazuaki Chayama
Jun 15, 2011·Gastrointestinal Endoscopy·Jeong-Sik ByeonJin-Ho Kim
May 2, 2012·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Ken OhataNobuyuki Matsuhashi
May 2, 2012·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Keiko NiimiKazuhiko Koike
Apr 1, 2014·Gastrointestinal Endoscopy Clinics of North America·Takashi ToyonagaTakeshi Azuma
Feb 6, 2015·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Shinji TanakaHisao Tajiri

❮ Previous
Next ❯

Citations

Feb 22, 2016·Gastrointestinal Endoscopy·Emmanuel C Gorospe, Louis M Wong Kee Song
Apr 21, 2017·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Koichi OkamotoTetsuji Takayama
Jun 26, 2017·Gastroenterology·Michael B WallaceAmit Rastogi
Nov 24, 2017·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Joaquín Rodríguez SánchezJosé Olmedo Camacho
Feb 28, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·J E EastB P Saunders
Dec 5, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Thomas R McCarty, Hiroyuki Aihara
Feb 15, 2020·The American Journal of Gastroenterology·Tonya KaltenbachDouglas K Rex
Sep 8, 2019·Digestive Diseases and Sciences·Nam Seok HamJeong-Sik Byeon
Sep 1, 2020·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Dong-Uk KangJeong-Sik Byeon
Apr 29, 2020·Surgical Endoscopy·Tak Lit Derek FungKam Hung Kwok
Oct 6, 2020·Endoscopy International Open·Mohamed Saleh IsmailMohamed O Othman
Oct 24, 2020·Therapeutic Advances in Gastroenterology·Giuseppe VanellaGuido Costamagna
Sep 22, 2020·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Harold Benites GoñiMilagros Dávalos Moscol
Mar 14, 2021·Gastrointestinal Endoscopy·Sehrish Jamot, Richard Rothstein
Apr 29, 2021·Expert Review of Gastroenterology & Hepatology·Mitsuru EsakiTakuji Gotoda
Jul 2, 2021·World Journal of Gastrointestinal Surgery·Mitsuru EsakiYoshihiro Ogawa
Aug 12, 2021·Clinical and Experimental Gastroenterology·Tara Keihanian, Mohamed O Othman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.