Optimized Particle Swarm Optimization (OPSO) and its application to artificial neural network training

BMC Bioinformatics
Michael MeissnerGisbert Schneider

Abstract

Particle Swarm Optimization (PSO) is an established method for parameter optimization. It represents a population-based adaptive optimization technique that is influenced by several "strategy parameters". Choosing reasonable parameter values for the PSO is crucial for its convergence behavior, and depends on the optimization task. We present a method for parameter meta-optimization based on PSO and its application to neural network training. The concept of the Optimized Particle Swarm Optimization (OPSO) is to optimize the free parameters of the PSO by having swarms within a swarm. We assessed the performance of the OPSO method on a set of five artificial fitness functions and compared it to the performance of two popular PSO implementations. Our results indicate that PSO performance can be improved if meta-optimized parameter sets are applied. In addition, we could improve optimization speed and quality on the other PSO methods in the majority of our experiments. We applied the OPSO method to neural network training with the aim to build a quantitative model for predicting blood-brain barrier permeation of small organic molecules. On average, training time decreased by a factor of four and two in comparison to the other PSO me...Continue Reading

References

Feb 22, 2002·Journal of Medicinal Chemistry·Dimitris K Agrafiotis, Walter Cedeño
Jan 18, 2003·Journal of Pharmaceutical Sciences·Mario LobellGyörgy M Keserü
Sep 19, 2003·Journal of Computer-aided Molecular Design·Walter Cedeño, Dimitris K Agrafiotis
Apr 8, 2004·Journal of Computer-aided Molecular Design·Uli FechnerGisbert Schneider

❮ Previous
Next ❯

Citations

Feb 12, 2015·The Journal of Chemical Physics·Yanchao Wang, Yanming Ma
Dec 14, 2007·Proceedings of the National Academy of Sciences of the United States of America·Michael Schmuker, Gisbert Schneider
Sep 24, 2013·IEEE Journal of Biomedical and Health Informatics·Tao PengXiaobo Zhou
Aug 24, 2011·IEEE Transactions on Neural Networks·Saman Razavi, Bryan A Tolson
Sep 22, 2010·Algorithms for Molecular Biology : AMB·Ming ZhengYan Wang
Jun 27, 2009·Neural Networks : the Official Journal of the International Neural Network Society·Serkan KiranyazMoncef Gabbouj
Oct 7, 2008·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Jian LiuXiaoping Luo
Dec 23, 2017·International Journal of Molecular Sciences·Liang-Yong XiaYong Liang
Nov 8, 2007·Chemical Biology & Drug Design·Vigneshwaran Namasivayam, Robert Günther
Dec 30, 2009·Biotechnology Progress·Li-Yeh ChuangCheng-Hong Yang
Oct 12, 2011·Chemical Biology & Drug Design·Vigneshwaran NamasivayamJürgen Bajorath
Aug 6, 2016·Molecular Informatics·Erik GawehnGisbert Schneider
Mar 19, 2020·Current Pharmaceutical Design·Kleber Santiago SilvaMaristela Pereira
Feb 24, 2007·Journal of Chemical Information and Modeling·Uli Fechner, Gisbert Schneider
Jul 2, 2008·Journal of Chemical Information and Modeling·Andreas Schüller, Gisbert Schneider
Jul 12, 2019·Chemical Reviews·Xin YangShengyong Yang

❮ Previous
Next ❯

Software Mentioned

OPSO
CPSO
gecco
MATLAB Neural Network Toolbox
PsoVis
CLIFF
MathType
PSO
speedCATS

Related Concepts

Related Feeds

Blood Brain Barrier Regulation in Health & Disease

The blood brain barrier is essential in regulating the movement of molecules and substances in and out of the brain. Disruption to the blood brain barrier and changes in permeability allow pathogens and inflammatory molecules to cross the barrier and may play a part in the pathogenesis of neurodegenerative disorders. Here is the latest research in this field.

Blood Brain Barrier Chips

The blood brain barrier (BBB) is comprised of endothelial cells that regulate the influx and outflux of plasma concentrations. Lab-on-a-chip devices allow scientists to model diseases and mechanisms such as the passage of therapeutic antibodies across the BBB. Discover the latest research on BBB chips here.

Blood Brain Barrier

The blood brain barrier is a border that separates blood from cerebrospinal fluid. Discover the latest search on this highly selective semipermeable membrane here.

Related Papers

Neural Networks : the Official Journal of the International Neural Network Society
Hong Zhang, Masumi Ishikawa
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
Qi ShenBao-xian Ye
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Fang YiLiu Li
© 2021 Meta ULC. All rights reserved