PMID: 8945040Nov 1, 1996Paper

Optimized standby rate reduces the ventricular rate variability in pacemaker patients with atrial fibrillation

Pacing and Clinical Electrophysiology : PACE
S E GreenhutW Hughes

Abstract

Patients with chronic atrial fibrillation (AF) and symptomatic bradycardia often receive ventricular-based pacemakers. However, many of these patients continue to have symptoms of palpitations, which may be due to ventricular rate variability. It has previously been shown that continuous ventricular pacing during AF has a stabilizing effect on the ventricular rate. Hence, a study was initiated to determine whether a patient-specific optimal ventricular standby rate that reduces the ventricular rate variability, without over-pacing, could be predicted. A ventricular rate stabilization (VRS) pacing algorithm that increases the pacing rate until instability is reduced below a threshold was developed. The VRS algorithm was utilized to determine a patient-specific standby rate in 15 patients with chronic AF, intact AV nodal conduction, and implanted pacemakers. The computer algorithm controlled a pacemaker programmer to automatically change the pacemaker's ventricular pacing rate via telemetry. Patients were studied for 15 minutes with VRS and for 15 minutes with 50 ppm fixed rate pacing (control). The results were as follows: (1) VRS versus control = P < 0.05; (2) mean ventricular pacing rate (ppm): 77 +/- 13 versus 50 +/- 0; (3) m...Continue Reading

Citations

Oct 25, 2006·Expert Opinion on Pharmacotherapy·Piotr RucinskiAndrzej Kutarski
Mar 19, 2004·Journal of Cardiovascular Electrophysiology·Michael O SweeneyUNKNOWN MOST Investigators
Aug 19, 2006·IEEE Transactions on Bio-medical Engineering·Jie LianVolker Lang
Apr 27, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Youhua Zhang, Todor N Mazgalev
May 11, 1999·Pacing and Clinical Electrophysiology : PACE·J K LeeN M Van Hemel
May 18, 2007·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Jie LianVolker Lang
Mar 31, 2007·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Jie LianVolker Lang

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