Optimizing colorectal cancer screening by race and sex: Microsimulation analysis II to inform the American Cancer Society colorectal cancer screening guideline

Cancer
Reinier G S MeesterIris Lansdorp-Vogelaar

Abstract

Colorectal cancer (CRC) risk varies by race and sex. This study, 1 of 2 microsimulation analyses to inform the 2018 American Cancer Society CRC screening guideline, explored the influence of race and sex on optimal CRC screening strategies. Two Cancer Intervention and Surveillance Modeling Network microsimulation models, informed by US incidence data, were used to evaluate a variety of screening methods, ages to start and stop, and intervals for 4 demographic subgroups (black and white males and females) under 2 scenarios for the projected lifetime CRC risk for 40-year-olds: 1) assuming that risk had remained stable since the early screening era and 2) assuming that risk had increased proportionally to observed incidence trends under the age of 40 years. Model-based screening recommendations were based on the predicted level of benefit (life-years gained) and burden (required number of colonoscopies), the incremental burden-to-benefit ratio, and the relative efficiency in comparison with strategies with similar burdens. When lifetime CRC risk was assumed to be stable over time, the models differed in the recommended age to start screening for whites (45 vs 50 years) but consistently recommended screening from the age of 45 year...Continue Reading

References

May 1, 1979·Cancer·R R RickertJ M Frasca
Sep 1, 1989·Scandinavian Journal of Gastroenterology·L G JohannsenN O Jacobsen
Aug 15, 1985·International Journal of Cancer. Journal International Du Cancer·J C ClarkJ G Simpson
Feb 1, 1997·Gastroenterology·S J WinawerR J Mayer
Feb 6, 2003·Journal of the National Cancer Institute·Nicolle M GattoAlfred I Neugut
Feb 26, 2009·The American Journal of Gastroenterology·Douglas K RexUNKNOWN American College of Gastroenterology
May 27, 2009·Gastrointestinal Endoscopy·Iris Lansdorp-VogelaarJ Dik F Habbema
Jun 17, 2009·Annals of Internal Medicine·Joan L WarrenDavid F Ransohoff
Jun 16, 2011·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Karen M KuntzAnn G Zauber
Aug 20, 2011·Journal of the National Cancer Institute·Nereo SegnanUNKNOWN SCORE Working Group
Apr 12, 2012·Archives of Internal Medicine·John M InadomiRodney A Hayward
Nov 1, 2013·Journal of the National Cancer Institute·Carolyn M RutterDeborah Schrag
Aug 15, 2014·JAMA : the Journal of the American Medical Association·Øyvind HolmeGeir Hoff
Nov 7, 2014·The American Journal of Gastroenterology·Peter S Liang, Jason A Dominitz
Dec 3, 2014·The American Journal of Gastroenterology·Douglas K RexDavid S Weinberg
Dec 3, 2014·JAMA : the Journal of the American Medical Association·Sameer D SainiSandeep Vijan
Jan 10, 2016·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Carolyn M RutterIris Lansdorp-Vogelaar
Jan 27, 2016·Annals of Internal Medicine·Christopher D JensenPauline A Mysliwiec
May 18, 2016·JAMA : the Journal of the American Medical Association·Sidney J WinawerBernard Levin
Jun 15, 2016·The American Journal of Gastroenterology·Ankie ReumkensSilvia Sanduleanu
Jun 16, 2016·JAMA : the Journal of the American Medical Association·UNKNOWN US Preventive Services Task ForceAlbert L Siu
Jun 16, 2016·JAMA : the Journal of the American Medical Association·Amy B KnudsenKaren M Kuntz
Mar 2, 2017·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
Apr 5, 2017·Journal of the National Cancer Institute·Rebecca L SiegelAhmedin Jemal
May 4, 2017·Gastroenterology·Caitlin C MurphyRobert S Sandler

❮ Previous
Next ❯

Citations

Nov 20, 2018·CA: a Cancer Journal for Clinicians·Richard C WenderRobert A Smith
Oct 1, 2019·Cancer·Whitney F JonesPaul C Schroy
Aug 12, 2020·Clinical Journal of Gastroenterology·Keiji MatsudaYuko Sasajima
May 18, 2019·Current Gastroenterology Reports·Caitlin C Murphy
Jun 19, 2019·World Journal of Gastroenterology : WJG·Alessandro MannucciGiulia Martina Cavestro
Dec 13, 2019·Journal of Cancer Epidemiology·Holli A Loomans-Kropp, Asad Umar
Sep 25, 2020·Clinics in Colon and Rectal Surgery·Blake Read, Patricia Sylla
Feb 11, 2020·JCO Oncology Practice·Y Nancy YouDavid Shibata
Aug 8, 2020·Journal of the National Cancer Institute·Elisabeth F P PeterseIris Lansdorp-Vogelaar
Mar 4, 2021·The American Journal of Gastroenterology·Aasma ShaukatDouglas K Rex
Apr 10, 2021·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Steffie K NaberIris Lansdorp-Vogelaar
Apr 11, 2021·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Emi NaslaziInge M C M de Kok
Jul 20, 2020·Gastroenterology·Christopher J Phillips, Robert E Schoen
Aug 25, 2021·Tropical Doctor·Shamir O CawichMilton Arthurs
Aug 31, 2021·International Journal of Cancer. Journal International Du Cancer·Iris Lansdorp-VogelaarCarlo Senore

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Software Mentioned

MISCAN
MISCAN Microsimulation Screening Analysis
Microsimulation Screening Analysis
Simulation Model of
Colon
SimCRC
SimCRC Simulation Model of

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.