Optimizing duodenoscope reprocessing: rigorous assessment of a culture and quarantine protocol

Gastrointestinal Endoscopy
Jennifer T HigaAndrew S Ross

Abstract

Iatrogenic infections related to duodenoscopes remain a top concern for medical centers where ERCP is performed. We assessed the long-term results and impact of key interventions in the optimization of a rigorous "culture and quarantine" program for duodenoscope reprocessing. We reviewed a prospectively collected, quality assurance database of all duodenoscope cultures (n = 4307) obtained for the initial 3-year duration of culture and quarantine from 2014 to 2017 in a single U.S.-based, high-volume endoscopy center. All duodenoscopes were subject to manual cleaning and automated reprocessing and drying, followed by sampling using a modified protocol developed by the Centers for Disease Control and Prevention. Duodenoscopes were cultured per-use. A total of 4307 duodenoscope cultures were obtained during the study period. High-concern organisms were isolated from 33 of these cultures, resulting in a .697% high-level disinfection defect rate. Statistically significant interventions included withdrawal of a high-frequency culture-positive duodenoscope (scope A) from clinical service in addition to implementation of new manufacturer-recommended cleaning protocols. Withdrawal of a second high-frequency culture-positive duodenoscope ...Continue Reading

Citations

Oct 23, 2018·Journal of Gastroenterology and Hepatology·Benedict M DevereauxRajvinder Singh
Sep 5, 2019·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Gheorghe G BalanAnca Trifan
Jun 28, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gheorghe G BalanCatalin Victor Sfarti
Sep 22, 2020·EClinicalMedicine·Sara LarsenAnders Mærkedahl
Sep 7, 2020·Gastrointestinal Endoscopy Clinics of North America·Monique T Barakat, Subhas Banerjee
Mar 21, 2021·Gastrointestinal Endoscopy·Sushrut Sujan Thiruvengadam, V Raman Muthusamy
Apr 17, 2021·Digestive Diseases and Sciences·Eric SweiAugustin Attwell
Oct 27, 2020·Techniques and Innovations in Gastrointestinal Endoscopy·Tiffany ChuaSofiya Reicher
Dec 24, 2020·Gastrointestinal Endoscopy·Lukejohn W DaySachin Wani
Sep 7, 2021·Gastrointestinal Endoscopy·Mark A Gromski, Stuart Sherman

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