Optimizing Electrode Montages of Transcranial Direct Current Stimulation for Attentional Bias Modification in Early Abstinent Methamphetamine Users

Frontiers in Pharmacology
Alireza ShahbabaieMichael A Nitsche

Abstract

Introduction: Chronic use of most psychoactive drugs may lead to substance dependence and drug addiction. Drug addiction is a chronically relapsing disorder, and current pharmacological and behavioral therapies are not fully efficient. Attentional bias (AB) is hypothesized to have a causal contribution to substance abuse, addiction development and, maintenance. Transcranial direct current stimulation (tDCS) has been of increasing interest in the past few years as a means for modulating neuroplasticity of the human brain. Although several studies have reported promising therapeutic effects for tDCS in drug abusers, there is no consensus about optimal electrode montages and target brain regions. This study was aimed to compare effectiveness of several electrode montages in modifying AB. Methods and Materials: Ninety early-abstinent methamphetamine users were recruited from several residential drug-rehabilitation centers in Tehran province. They were randomly assigned to six groups with different electrode montages, targeting the left or right dorsolateral prefrontal cortex (DLPFC) as follows: Two conditions with anodal tDCS over the right DLPFC (return electrode placed over the left shoulder or left supraorbital ridge), three con...Continue Reading

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Citations

Oct 20, 2018·Frontiers in Psychiatry·Eun Jin KimKee-Hong Choi
Oct 22, 2020·Medical Engineering & Physics·Cassandra D Solomons, Vivekanandan Shanmugasundaram
Nov 5, 2020·Progress in Neuro-psychopharmacology & Biological Psychiatry·Hyun Joon Kim, Nyeonju Kang
Dec 5, 2019·NeuroImage. Clinical·Jennifer L StewartMartin P Paulus
Nov 13, 2019·Progress in Neuro-psychopharmacology & Biological Psychiatry·Juliana Teti MayerDjamila Bennabi
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Oct 26, 2021·Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology·Jaber AlizadehgoradelMina Taherifard

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