Optimizing immobilization, margins, and imaging for lung stereotactic body radiation therapy

Translational Lung Cancer Research
Jason K MolitorisCharles B Simone

Abstract

The simultaneous advancement of technologies for the delivery of precisely targeted radiation therapy and the paradigm shift to substantial hypofractionation have led to significant improvements in the treatment of early stage non-small cell lung cancer (ES-NSCLC). Stereotactic body radiation therapy (SBRT) has become a well-established option for the treatment of ES-NSCLC and is now becoming widely available within the radiation oncology community. Implementation of this technique, however, requires highly accurate target delineation, thorough evaluation of tumor motion, and improved on-board imaging at the time of treatment for patient alignment, each of which is critical for successful tumor control and mitigation of risks to normal tissues. In this article, we review updates and issues related to immobilization and image guidance for SBRT in the treatment of ES-NSCLC.

Citations

Mar 17, 2020·Journal of Applied Clinical Medical Physics·Justin D GagneurYi Rong
Jul 10, 2020·Journal of Applied Clinical Medical Physics·Parisa SadeghiJames L Robar
Oct 17, 2019·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·D GensanneS Thureau
Jun 27, 2021·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Hatim FakirJoanna Laba
Jul 22, 2021·Current Oncology·Enrique GutiérrezAlexander Sun

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