PMID: 8961363Oct 1, 1996Paper

Optimizing radiotherapy of the internal mammary chain in breast carcinoma by scintigraphy

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
H Struikmans, P P van Rijk

Abstract

The reduction in breast cancer death, as reported in recent trials, was found to be significant and techniques of minimizing cardiac dose were found to be important. The purpose of our study was to investigate the location of the internal mammary chain (IMC) both in the lateral and dorsal direction, in primary breast cancer patients. In 320 female breast cancer patients a scintigram of the IMC (IMC-s) was performed. Lateralisation and depth were determined. Special attention was paid to the consequences of the use of fixed target volumes. Lateralisation was determined in 281 patients, with a mean of 33.9 mm. Depth was determined in 266 patients, with a mean of 31.0 mm. We showed, that the location of the IMC lymph nodes varies considerably, both in the lateral and in the dorsal direction. The maximum values of the lateralisation and the corresponding depth did not correlate. Using electron beam therapy, a fixed target volume defined by a (ipsi)lateralisation of 50 mm and a dose specification on a depth of 30 mm was demonstrated to include the IMC adequately, in 12% of all cases. The use of fixed target volumes in the radiotherapy of the IMC in breast cancer patients is inappropriate. We recommend performing an IMC-s, in treatme...Continue Reading

Citations

Aug 22, 2001·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Y LievensW Van den Bogaert
Apr 9, 2002·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·H StruikmansJ W van Isselt
Nov 22, 2002·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Anne E SaarnakSara H Muller
Jul 13, 2000·International Journal of Radiation Oncology, Biology, Physics·C W HurkmansI A Bruinvis
Jul 4, 1998·International Journal of Radiation Oncology, Biology, Physics·J C ChengA T Huang
Oct 7, 2008·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Camila Trevisan PereiraPedro Primo Bombonato
Jun 3, 2004·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ivessa M DijkemaBerend Hillen
May 10, 2008·Acta Oncologica·Mette S ThomsenUNKNOWN Danish Breast Cancer Cooperative Group
Nov 6, 2020·The Lancet Oncology·Philip M PoortmansUNKNOWN European Organisation for Research and Treatment of Cancer Radiation Oncology and Breast Cancer Groups

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