Optimizing the response from a passively controlled biventricular assist device

Artificial Organs
Nicholas Richard GaddumMark Pearcy

Abstract

Recent studies into rotary biventricular support have indicated that inadequate left/right flow balancing may lead to vascular congestion and/or ventricular suckdown. The implementation of a passive controller that automatically adjusts left/right flow during total and partial cardiac support would improve physiological interaction. This has encouraged the development of a biventricular assist device (BiVAD) prototype that achieves passive control of the two rotary pumps' hydraulic output by way of a nonrotating double pressure plate configuration, the hub, suspended between the ventricular assist device (VAD) impellers. Fluctuations in either the VAD's inlet or outlet pressure will cause the hub to translate, and in doing so, affect each pump's hydraulic outputs. In order to achieve partial support, the floating assembly needed to respond to pathologic blood pressure signals while being insensitive to residual ventricular function. An incorporated mechanical spring-mass-damper assembly affects the passive response to optimize the dynamic interaction between the prototype and the supported cardiovascular system. It was found that increasing the damping from a medium to a high level was effective in filtering out the higher freq...Continue Reading

References

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Oct 31, 2008·Artificial Organs·Daniel TimmsMark Pearcy
May 21, 2010·Artificial Organs·Nicholas Richard GaddumMark John Pearcy

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Citations

Mar 16, 2011·Artificial Organs·Paul S Malchesky
Aug 1, 2012·Artificial Organs·Nicholas Richard GaddumDaniel Lee Timms
Aug 14, 2012·Artificial Organs·Shaun David GregoryDaniel Timms
Jan 1, 2014·Artificial Organs·Nicholas R GaddumRobert Salamonsen
Sep 25, 2017·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Yu WangGuruprasad A Giridharan
Aug 19, 2015·Annals of Biomedical Engineering·Jo P PaulsShaun D Gregory

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