PMID: 11929011Apr 4, 2002Paper

Optimizing the shape of ultrasound transducers for interstitial thermal ablation

Medical Physics
C LafonD Cathignol

Abstract

Heat deposition by interstitial routes, especially with ultrasound-based instruments, is becoming a valuable therapeutic option for the treatments of sites, which are difficult to access from outside of the body. The active part of most interstitial ultrasound applicators described in the literature is logically tubular to induce cylindrical volumes of coagulation necrosis. Because the pressure generated by such tubular transducers falls off rapidly with radial distance, we previously proposed using a rotating plane transducer. For a plane wave, the pressure fall-off is only due to attenuation, which makes deeper lesions and shorter treatment times possible. This work represents an advance in the development of ultrasound applicators designed for interstitial applications. This new applicator used a rotating slightly focused transducer. A brief theoretical analysis resulted in the choice of a long focal distance of 22 mm to obtain a nearly constant pressure all along the therapeutic depth. To experimentally validate this focal distance, pressure measurements were made in a tissue mimicking liquid phantom and the results were compared with those obtained with a plane transducer. In vitro experiments showed that necrosis could be...Continue Reading

References

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Citations

Sep 8, 2011·Biomedical Microdevices·Karthik VisvanathanYogesh B Gianchandani
Jul 15, 2005·Medical Physics·Anthony B RossDonna M Bouley
Nov 4, 2005·The Journal of the Acoustical Society of America·T Douglas MastMichael H Slayton
Aug 10, 2013·Medical Physics·David SchlesingerJames Larner
Aug 9, 2011·Ultrasound in Medicine & Biology·T Douglas MastSteven M Rudich
May 6, 2010·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Guillaume BouchouxCyril Lafon
Nov 16, 2005·Ultrasound in Medicine & Biology·Inder Raj S MakinMichael H Slayton
Jun 7, 2013·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Punit PrakashChris J Diederich
Jun 21, 2007·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·C LafonJ Y Chapelon

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