Optimizing ultrasound focus distributions for hyperthermia

IEEE Transactions on Bio-medical Engineering
R J Lalonde, J W Hunt

Abstract

A method is described for generating ultrasound focus patterns for ultrasound hyperthermia treatment planning for steady state and transient hyperthermia. The solution for placement and intensity of ultrasound focus points is based on two types of temperature constraints: 1) equality constraints on the tumor boundary (temperature is held at maximum safe level) and 2) inequality constraints in the tumor interior (in a therapeutic range of temperatures). The method employs a simplex algorithm to solve a series of linear equations which approximate the heating distribution in tissue. Examples are given for field conjugate acoustic lens applicators capable of generating multiple foci simultaneously.

References

Aug 1, 1992·IEEE Transactions on Bio-medical Engineering·B J James, D M Sullivan
Jan 1, 1992·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·W L LinK Hynynen
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Jan 1, 1987·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·K HynynenT Cetas
May 1, 1987·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·K B Ocheltree, L A Frizzell
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Citations

Aug 26, 1999·Ultrasound in Medicine & Biology·C J Diederich, K Hynynen
Aug 5, 1998·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·I S Khalil-BustanyC Kirjner-Neto

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