Optimum duration of regimens for Helicobacter pylori eradication

The Cochrane Database of Systematic Reviews
Yuhong YuanPaul Moayyedi

Abstract

The optimal duration for Helicobacter pylori (H. pylori) eradication therapy is controversial, with recommendations ranging from 7 to 14 days. Several systematic reviews have attempted to address this issue but have given conflicting results and limited their analysis to proton pump inhibitor (PPI), two antibiotics (PPI triple) therapy. We performed a systematic review and meta-analysis to investigate the optimal duration of multiple H. pylori eradication regimens. The primary objective was to assess the relative effectiveness of different durations (7, 10 or 14 days) of a variety of regimens for eradicating H. pylori. The primary outcome was H. pylori persistence. The secondary outcome was adverse events. The Cochrane Library, MEDLINE, EMBASE, and CINAHL were searched up to December 2011 to identify eligible randomised controlled trials (RCTs). We also searched the proceedings of six conferences from 1995 to 2011, dissertations and theses, and grey literature. There were no language restrictions applied to any search. Only parallel group RCTs assessing the efficacy of one to two weeks duration of first line H. pylori eradication regimens in adults were eligible. Within each regimen, the same combinations of drugs at the same d...Continue Reading

References

Oct 3, 1987·British Medical Journal·J CockburnR W Sanson-Fisher
Sep 1, 1986·Controlled Clinical Trials·R DerSimonian, N Laird
Feb 1, 1995·Alimentary Pharmacology & Therapeutics·G D BellC Brown
Dec 24, 1994·BMJ : British Medical Journal·C E CounsellP A Sandercock
Feb 18, 1995·BMJ : British Medical Journal·R J Cook, D L Sackett
Aug 1, 1995·European Journal of Gastroenterology & Hepatology·D Y Graham
Jan 1, 1996·Scandinavian Journal of Gastroenterology. Supplement·R H Hunt
Jan 13, 1997·Archives of Internal Medicine·J L TaylorJ W Freston
Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Feb 12, 1998·BMJ : British Medical Journal·M EggerA N Phillips
Apr 17, 1998·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·R Hunt, A B Thomson
May 7, 1998·Journal of Gastroenterology and Hepatology·N Dal Bo'M Rugge
Sep 16, 1998·Journal of Gastroenterology and Hepatology·S K Lam, N J Talley
May 20, 1999·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·R H HuntA B Thomson
May 29, 1999·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·R A JohnsonE Colombari
Sep 10, 1999·BMJ : British Medical Journal·S Hollis, F Campbell
Sep 28, 1999·Scandinavian Journal of Gastroenterology. Supplement·G Dusheiko
Nov 10, 2000·Zeitschrift für Gastroenterologie·G Treiber
Jan 6, 2001·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·A PilottoF Di Mario

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Citations

Nov 29, 2016·Scientific Reports·Iona K PatersonNick G H Taylor
Mar 1, 2017·Lancet·Angel Lanas, Francis K L Chan
Apr 10, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Muhammad Miftahussurur, Yoshio Yamaoka
Nov 12, 2015·World Journal of Gastrointestinal Pharmacology and Therapeutics·Su Young KimJun-Won Chung
Jun 28, 2019·Internal Medicine·Shu KiyotokiIsao Sakaida
Jan 28, 2020·Journal of Gastroenterology and Hepatology·Jyh-Ming LiouMing-Shiang Wu
Sep 15, 2019·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Sanjeev Kumar JhaRavish Ranjan
Sep 20, 2019·Journal of Cellular and Molecular Medicine·Yan Sun, Jun Zhang
May 4, 2017·Helicobacter·Javier P Gisbert, Adrian G McNicholl
May 18, 2017·Terapevticheskiĭ arkhiv·I G Maev, A N Kazyulin
Nov 15, 2016·Gut and Liver·Daniel S StrandDavid A Peura
Aug 2, 2017·Journal of Gastroenterology and Hepatology·Varocha MahachaiDavid Graham
Dec 27, 2019·Gut and Liver·Tiing Leong Ang, Daphne Ang
May 6, 2021·Journal of Primary Care & Community Health·Pedro CortésDana M Harris
Jul 16, 2021·Therapeutic Advances in Gastroenterology·Caiqi LiuTongsen Zheng

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