Optimum emission time in deep-inspiration breath-hold PET-CT: a preliminary result

Annals of Nuclear Medicine
Koichi MiyashitaTomio Inoue

Abstract

The purpose of this study was to investigate optimum emission time of deep inspiration breath-hold (DIBH) positron emission tomography-computed tomography (PET-CT). We collected 15 PET-CT data sets by adding data of every 10 s and acquisition time ranging from 10 s (1 x 10 s acquisition) to 150 s (15 x 10 s acquisition) for both of DIBH mode and free-breathing condition (continuous mode) in phantom study. The coefficient of variation (CV) of radioactivity concentration was compared to determine optimum emission time of PET-CT. We also compared images of DIBH mode and continuous mode to clarify the influence of diaphragmatic movement in clinical setting. The mean +/- SD of CV in DIBH mode was 1236.3 +/- 323.1. When compared with the CV at 120 s, the relative error of CV is within 10% at 110 s (0.204), 15% at 100 s (0.212), and 20% at 90 s (0.222), respectively. Optimum emission time greater than 90 s is required to obtain clinically available images in DIBH mode. In the clinical setting, the SUV of the lung base and measurements of uptake show little influence by respiration on DIBH PET-CT. Optimum emission time of DIBH technique greater than 90 s acquisition is preferable for clinical use.

References

Oct 28, 2003·Clinical Nuclear Medicine·Ismet SarikayaSteven M Larson
Jan 18, 2005·Medical Physics·S A NehmehJ L Humm
May 4, 2007·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Gustavo S P MeirellesHeiko Schöder
Jul 18, 2008·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Tsuyoshi KawanoTomio Inoue
Feb 12, 2009·Annals of Nuclear Medicine·Toshiaki YamaguchiKazunari Ishii
Sep 18, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Tatsuo TorizukaYasuomi Ouchi

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Citations

Mar 3, 2011·Medical Physics·S A NehmehJ L Humm
Nov 9, 2016·The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutica·Mariana ZirnsakMartin Freesmeyer

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