Options for prevention of HIV transmission from mother to child, with a focus on developing countries

Paediatric Drugs
Louise Kuhn, Ingrid Peterson

Abstract

Use of antiretroviral drugs among HIV-infected pregnant women in many developed countries has significantly reduced rates of mother-to-child HIV transmission, demonstrating that this route of transmission is amenable to intervention. Prevention of transmission in developing countries has proved to be more difficult, although recent advances in short-course antiretroviral drug interventions have made it an immediate possibility, rather than a distant hope as it was seen to be in the recent past. Non-antiretroviral drug interventions, including washing of the birth canal with antiseptic solution and micronutrient supplementation, have not been found to be effective at interrupting mother-to-child HIV transmission, but may have other benefits for maternal and child health. An important issue for developing countries is prevention of postnatal HIV transmission through breast feeding. In most developing countries, formula feeding is not a reasonable option, given the higher rates of mortality from diarrheal and respiratory disease associated with avoidance of all breast feeding. A promising new line of research has recently been broached with the findings from a study in South Africa, which demonstrated that exclusive breast feeding...Continue Reading

References

Oct 22, 1992·The New England Journal of Medicine·Y J BrysonD W Wara
Oct 1, 1992·The Pediatric Infectious Disease Journal·P LepageF Dabis
Jan 1, 1991·AIDS Research and Human Retroviruses·H Mano, J C Chermann
May 1, 1991·Journal of Virology·N Amirhessami-Aghili, S A Spector
May 1, 1991·The Journal of Pediatrics·A S CunninghamE F Jelliffe
Mar 1, 1991·AIDS Research and Human Retroviruses·V CourgnaudC Bréchot
Nov 1, 1990·American Journal of Public Health·S J Heymann
Apr 1, 1989·American Journal of Epidemiology·R E BlackH C Kanashiro
Mar 26, 1988·British Medical Journal·A BriendM G Rowland
Feb 1, 1986·American Journal of Epidemiology·J P HabichtW P Butz
Dec 1, 1995·The Journal of Infectious Diseases·C LangstonW T Shearer
May 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L M FrenkelR C Reichman
Aug 1, 1995·American Journal of Public Health·A CoutsoudisZ A Stein
Aug 1, 1995·American Journal of Obstetrics and Gynecology·H MinkoffA D Willoughby
Sep 1, 1993·The Journal of Infectious Diseases·A M KessonA L Cunningham
Jan 1, 1995·Paediatric and Perinatal Epidemiology·L Kuhn, Z A Stein
Feb 1, 1996·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·P M WortleyS Davis
Jun 1, 1997·American Journal of Public Health·L Kuhn, Z Stein

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Citations

Jan 8, 2004·Reproductive Health Matters·Maria de Bruyn
Jul 3, 2007·SAHARA J : Journal of Social Aspects of HIV/AIDS Research Alliance·I A MothD O Kaseje
Dec 1, 2010·African Journal of AIDS Research : AJAR·Stephen Muoki Joshua
Sep 12, 2003·Emerging Infectious Diseases·Aimin Chen, Walter J Rogan
Mar 7, 2006·Health Economics·Martin BrowningEskil Heinesen

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