Oral and intravenous steroids in giant cell arteritis

Clinical & Experimental Ophthalmology
Colin C K Chan, Justin O'Day

Abstract

Giant cell arteritis can result in devastating visual loss. Treatment with steroids does result in visual recovery in some patients but the exact percentage is unknown. Intravenous megadose steroids appear to offer some advantage over oral steroids presumably through non-genomic effects, which manifest at doses of 500 mg or more. Side-effects are more likely in the elderly especially those with renal and cardiac co-morbidities. The authors' current recommendation is that intravenous steroids should be given to patients with established visual loss or amaurosis fugax.

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Citations

Mar 1, 2006·Rheumatic Diseases Clinics of North America·Curry L Koening, Carol A Langford
Jun 6, 2003·Clinical & Experimental Ophthalmology·Helen Danesh-Meyer
Sep 15, 2006·Clinical & Experimental Ophthalmology·Olivia C MorrisJustin O'Day
Apr 22, 2006·Clinical & Experimental Ophthalmology·Stuart C CarrollHelen V Danesh-Meyer
Oct 22, 2008·Acta Ophthalmologica·Aki Kawasaki, Valerie Purvin
Oct 23, 2010·Neurología : publicación oficial de la Sociedad Española de Neurología·J Balsalobre Aznar, J Porta-Etessam
Jul 2, 2005·The Neurologist·Valerie Purvin, Aki Kawasaki
Mar 26, 2021·Neuro-ophthalmology·Amritha KanakamedalaAndrew G Lee

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