Oral and salivary changes in patients with chronic kidney disease: A clinical and biochemical study

Journal of Indian Society of Periodontology
Beela Ram AnuradhaSwati Penumarty

Abstract

Both chronic kidney disease (CKD) and its treatment can affect a wide range of tissues and systems. It directly or indirectly affects flow, concentrations and composition of saliva. Hemodialysis can effectively minimize most of these complications to some extent. The main aim of this study was to know the salivary content of sodium, potassium, calcium, urea, bicarbonate and oral manifestations in patients with CKD. For this study, 50 patients diagnosed with CKD and 50 systemically and periodontally healthy individuals were subjected to a detailed general and intraoral examination. Whole un-stimulated saliva samples of all the selected subjects were collected and subjected to calcium (Ca), phosphorous (P), sodium (Na), potassium (K), bicarbonate and urea analysis. Paired t-test, Mann-Whitney test. Among 50 study subjects, 26 subjects had reduced salivary flow in the range of 0.1-0.4 ml/min. Intraoral examination of the study subjects revealed pallor, increased deposition of calculus, bleeding gums, metallic taste, hypoplasia of teeth and fissured tongue. There was a significant difference between healthy and prehemodialysis patients in the salivary sodium, potassium, calcium, phosphorus, urea levels and the difference was insign...Continue Reading

Citations

Sep 25, 2017·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Jéssica Antoniana Lira E SilvaSérgio d'Ávila
Dec 25, 2018·International Journal of Dental Hygiene·Thuy A V Pham, Dinh D Le
Apr 29, 2020·Bioanalysis·Yanisa ThepchuayAntónio Oss Rangel
Apr 25, 2020·International Journal of Molecular Sciences·Izabella MogilnickaMarcin Ufnal
Mar 4, 2021·Medicine·Jia-Ming ChenLun-Chien Lo
Mar 22, 2021·Lasers in Medical Science·Vanessa Christina Santos PavesiAlessandro Melo Deana

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