Oral Antibiotics and Abscess Formation After Appendectomy for Perforated Appendicitis in Children.

The Journal of Surgical Research
Alex J GordonSandra Tomita

Abstract

There is little consensus regarding the use of postoperative antibiotics in the management of perforated appendicitis in children. Patients are commonly discharged with oral antibiotics after a course of intravenous antibiotics; however, recent literature suggests that patients can be safely discharged without any oral antibiotics. To further evaluate this protocol, we conducted a multicenter retrospective preimplementation/postimplementation study comparing rates of abscess formation and rehospitalization between patients discharged with and without oral antibiotics. We reviewed the records of all pediatric patients who underwent appendectomies for perforated appendicitis at NYU Tisch Hospital, Bellevue Hospital, and Hackensack University Medical Center from January 2014 to June 2019. Data pertaining to patient demographics, hospital course, intraoperative appearance of the appendix, antibiotic treatment, abscess formation, and rehospitalization were collected. A total of 253 patients were included: 162 received oral antibiotics and 91 did not. The median length of antibiotic treatment (oral and intravenous) was 11 (10-14) d for patients on oral antibiotics and 5 (3-6) d for patients without oral antibiotics (P < 0.01). The me...Continue Reading

References

Nov 1, 1981·Drug Intelligence & Clinical Pharmacy·M H Stranz, W E Bradley
Jun 30, 2000·Annals of Emergency Medicine·S G Rothrock, J Pagane
Jul 6, 2000·Pediatrics·L B DusdiekerG Milavetz
Feb 22, 2003·Journal of the American College of Surgeons·Catherine ChenSusan K Parsons
Mar 26, 2010·Scandinavian Journal of Gastroenterology·Samuel Andreas KäserChristoph Andreas Maurer
Dec 3, 2015·Journal of Pediatric Surgery·Veerle A B van den BogaardPeter de Winter
Jan 30, 2016·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·G FrongiaP Günther

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Citations

Dec 20, 2020·The Journal of Surgical Research·Talal B SeddikHayden T Schwenk
Jul 22, 2021·Infectious Diseases and Therapy·Alex S PlattnerBaddr A Shakhsheer

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