Oral antibiotics versus parenteral antibiotics for severe pneumonia in children.

The Cochrane Database of Systematic Reviews
M X Rojas, C Granados

Abstract

Acute respiratory infection (ARI) is one of the leading causes of morbidity and mortality in children under five years of age in developing countries. When hospitalisation is required, the usual practice includes administering parenteral antibiotics if a bacterial infection is suspected. This has disadvantages as it causes pain and discomfort to the children, which may lead to treatment refusal or reduced compliance. It is also associated with needle-related complications. In some settings this equipment is in short supply or unavailable necessitating transfer of the child, which increases risks and healthcare costs. To determine the equivalence in effectiveness and safety of oral antibiotic compared to parenteral antibiotic therapies in the treatment of severe pneumonia in children between three months and five years of age. We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library Issue 2, 2005); MEDLINE (January 1966 to July 2005); EMBASE (January 1990 to July 2005) and LILACS (February 2005). The review included published or unpublished randomised controlled trials (RCTs) and quasi-RCTs comparing any oral antibiotic therapy with any parenteral antibiotic therapy for the treatment of seve...Continue Reading

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Citations

Apr 20, 2012·Journal of the Medical Library Association : JMLA·Charlotte E Nash-StewartChris B Del Mar
Jul 20, 2018·The Cochrane Database of Systematic Reviews·Rashmi R DasSushree S Naik
Oct 26, 2011·Multiple Sclerosis : Clinical and Laboratory Research·Sabine SkrzipekAlexander Dressel
Jun 5, 2013·The Cochrane Database of Systematic Reviews·Rakesh LodhaRavindra M Pandey
Jun 18, 2010·The Cochrane Database of Systematic Reviews·Sally A KilburnRichard Brindle
Dec 22, 2010·Paediatric Respiratory Reviews·Varinder Singh, Satinder Aneja

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