Oral bowenoid papulosis in an HIV-positive male

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
Joseph RinaggioW C Lambert

Abstract

Bowenoid papulosis (BP) is a condition triggered by human papillomavirus infection and characterized by the development of 1 or more warty lesions, usually in the anogenital region. Although the oral cavity has been known to host several types of warts, thus far only 4 cases of BP have been reported in this anatomic site. We describe a 42-year-old male with AIDS who presented with numerous papillary lesions of the labial mucosa and vermilion. Biopsy yielded a diagnosis of BP. Treatment of the condition consisted of intralesional and subcutaneous injections of interferon-alpha followed by topical application of imiquimod 5% cream. Neither regimen resulted in resolution of the lesions. To our knowledge, this represents the first case of BP arising in the oral mucosa of an HIV-infected individual.

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Citations

Apr 20, 2013·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Sook-Bin WooMark A Lerman
Jun 7, 2011·Oral and Maxillofacial Surgery Clinics of North America·Raymond J Melrose
Sep 26, 2006·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Darren CoxJohn S Greenspan
Oct 1, 2019·Journal of Cutaneous Pathology·Jean C B FerreiraElismauro F Mendonça

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