Oral cholelitholysis--cheno versus urso: Japanese experience

Digestive Diseases and Sciences
F Nakayama

Abstract

The present status of the use of cholelitholytic agents in Japan is presented. Open and double-blind studies of chenodeoxycholic acid and ursodeoxycholic acid are compared with respect to their efficacy and safety. Although the in vitro solubilization of cholesterol with ursodeoxycholic acid seems to be less than with chenodeoxycholic acid, the higher dose of ursodeoxycholic acid which can be used because of the lack of side effects such as diarrhea and elevation of transaminases and a lower lithogenic index of bile obtainable favors ursodeoxycholic acid as an oral cholelitholytic agent at the moment.

References

Dec 1, 1977·The American Journal of Digestive Diseases·L J Schoenfield
Jan 1, 1977·Gastroenterologia Japonica·M OkumuraT Hisatsugu
Dec 9, 1972·Lancet·G D BellR H Dowling
Sep 27, 1973·The New England Journal of Medicine·J L Thistle, A F Hofmann
Jan 6, 1972·The New England Journal of Medicine·R G DanzingerJ L Thistle
Apr 1, 1971·The New England Journal of Medicine·K BissC B Taylor
Sep 1, 1957·A.M.A. Archives of Surgery·C G JOHNSTON, F NAKAYAMA
Nov 3, 1962·JAMA : the Journal of the American Medical Association·M L SIEVERS, J R MARQUIS

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Citations

Dec 1, 1984·Digestive Diseases and Sciences·K MiyazakiA Koga
Feb 1, 1987·American Journal of Surgery·H A PittT R Gadacz
Jan 1, 1982·Preparative Biochemistry·J D SutherlandT P Forrest
Jan 2, 1982·British Medical Journal·M C Bateson
Mar 1, 1990·Ohio Medicine : Journal of the Ohio State Medical Association·A Fink, D McFadden
Sep 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S M Strasberg, P A Clavien
Jan 1, 1985·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M M FisherS V Lee
Nov 1, 1982·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·E RodaL Barbara
Jul 3, 2013·The Cochrane Database of Systematic Reviews·Tao GanYiping Wang
Sep 1, 1982·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·T F ShaperoM M Fisher
Apr 1, 1993·Alimentary Pharmacology & Therapeutics·G R MayE A Shaffer

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