PMID: 10579115Dec 1, 1999

Oral complications associated with immunosuppression and cancer therapies

Infectious Disease Clinics of North America
J B Epstein, A W Chow

Abstract

The oral manifestations of oropharyngeal infection in immunocompromised patients present a particular challenge for both medical and dental professionals because clinical signs and symptoms may be minimal and accurate diagnosis and appropriate treatment may be difficult. Effective control of infection and management of oral symptoms are important and may be achieved by the judicious use of topical and systemic agents and by maintaining good oral hygiene. Prevention of mucosal breakdown, suppression of microbial colonization, control of viral reactivation, and effective management of severe xerostomia are all critical steps to reduce the overall morbidity and mortality of oromucosal infections in the severely immunocompromised patient.

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Related Concepts

Bacterial Infections
Candidiasis
Differential Diagnosis
Mouth Diseases
Buccal Mucosa
Malignant Neoplasms
Oral Mucositis
Virus Diseases
Immunocompromised Host

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