Oral contraceptive pill use and the susceptibility to markers of exercise-induced muscle damage

European Journal of Applied Physiology
K M HicksC I Morse

Abstract

Firstly, to establish whether oral contraceptive pill (OCP) users are more susceptible to muscle damage compared to non-users, and secondly, to establish whether differences can be attributed to differences in patella tendon properties. Nine female OCP users and 9 female non-users participated in the investigation. Combining dynamometry, electromyography and ultrasonography, patella tendon properties and vastus lateralis architectural properties were measured pre and during the first of 6 sets of 12 maximal voluntary eccentric knee extensions. Serum oestrogen levels were measured on the 7th day of the pill cycle and the 14th day of menstrual cycle in OCP users and non-users, respectively. Maximal voluntary isometric knee extension torque loss, creatine kinase and muscle soreness were measured 48 h pre-damage, post-damage, and 48, 96 and 168 h post-damage. Oestrogen levels were significantly lower in OCP users compared to non-users (209 ± 115 and 433 ± 147 pg/ml, respectively, p = 0.004). Proposed determinants of muscle damage, patella tendon stiffness and maximal eccentric torque did not differ between OCP users and non-users. The change in creatine kinase from pre to peak was significantly higher in OCP users compared to non-u...Continue Reading

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Citations

Nov 11, 2019·International Journal of Emergency Medicine·Gayatri Saxena, Ahmed Mahdi
Jun 19, 2020·Case Reports in Medicine·Neluwa Liyanage Ruwan IndikaPoruthotage Pradeep Rasika Perera
Nov 18, 2020·Journal of Strength and Conditioning Research·Nuria Romero-ParraUNKNOWN IronFEMME Study Group
Dec 19, 2020·Journal of Strength and Conditioning Research·Nuria Romero-ParraUNKNOWN IronFEMME Study Group

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