PMID: 11340105May 8, 2001Paper

Oral exposure to butter, but not fat replacers elevates postprandial triacylglycerol concentration in humans

The Journal of Nutrition
Richard D Mattes

Abstract

Oral exposure to dietary fat augments the postprandial triacylglycerol (TAG) concentration. We investigated the TAG response after oral exposure to butter and selected fat replacers. At 2200 h, 17 healthy adults consumed 80 g of almonds and fasted until 0700 h. Safflower oil (50 g in 1-g capsules) was then consumed. Oral stimulation was provided periodically for 2 h as potatoes, potatoes containing butter or one of three fat replacers or no oral stimulation in random order at weekly intervals. Blood was collected at stipulated intervals for 8 h. Oral exposure to butter led to a significantly longer postprandial TAG elevation than the other treatments. The results could not be explained by differential stimulus ingestion, palatability or perceived fat content. There was no significant treatment effect on concentrations of serum oleic acid, apolipoprotein (apo)B-48 or apoB-100, suggesting any oral exposure influence on release of dietary lipid stored in the lacteals or chylomicron and VLDL particle number contributed little to the postprandial TAG rise. In summary, oral exposure to butter elicited a greater postprandial TAG elevation than the tested fat replacers, possibly due to reduced TAG clearance.

References

Sep 1, 1979·Circulation·D B Zilversmit
Jan 1, 1979·Scandinavian Journal of Gastroenterology·T W SchwartzL Olbe
Nov 11, 1992·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·J R PatschW Patsch
Dec 1, 1991·Journal of the American College of Nutrition·J DupontE B Feldman
Jun 1, 1995·Current Opinion in Lipidology·F Karpe, A Hamsten
Apr 29, 1993·The New England Journal of Medicine·M H CriquiC E Davis
Nov 1, 1995·Diabetes Research and Clinical Practice·B GlasbrennerG Adler
Apr 1, 1997·The American Journal of Physiology·T A GilbertsonW T Monroe
May 1, 1997·Digestive Diseases and Sciences·M WøjdemannJ F Rehfeld
Jul 1, 1997·The Proceedings of the Nutrition Society·C M Williams
Feb 19, 1998·The American Journal of Gastroenterology·M WøjdemannO Olsen
Mar 21, 1998·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·S E DrummondT R Kirk
Jul 31, 1998·The British Journal of Nutrition·K EvansK N Frayn
May 21, 1999·Physiology & Behavior·M TsurutaT Fushiki
Jul 1, 1954·The Journal of Clinical Investigation·A I MENDELOFF

❮ Previous
Next ❯

Citations

Oct 17, 2001·Current Atherosclerosis Reports·E J Parks
Mar 31, 2006·The British Journal of Nutrition·Astrid J P G Smeets, Margriet S Westerterp-Plantenga
Jan 20, 2007·American Journal of Physiology. Gastrointestinal and Liver Physiology·Angela Chalé-RushRichard D Mattes
Mar 5, 2014·BioFactors·Robin M TuckerCordelia A Running
Oct 17, 2001·Journal of the American College of Nutrition·T J Tittelbach, R D Mattes
Jun 11, 2005·The British Journal of Nutrition·Tomonori UnnoKazuo Kondo
Dec 17, 2008·American Journal of Physiology. Gastrointestinal and Liver Physiology·Richard D Mattes
Nov 11, 2008·Annals of the New York Academy of Sciences·Dany GaillardPhilippe Besnard
Sep 26, 2008·The British Journal of Nutrition·Astrid J SmeetsMargriet S Westerterp-Plantenga
Feb 10, 2007·American Journal of Physiology. Gastrointestinal and Liver Physiology·Richard D Mattes
Jan 3, 2012·Journal of Lipid Research·Marta Yanina PepinoNada A Abumrad
Mar 12, 2005·Annals of Nutrition & Metabolism·Christiane SeidelGerhard Jahreis
Apr 19, 2003·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Takayuki Kawai, Tohru Fushiki
Jan 14, 2004·Journal of Atherosclerosis and Thrombosis·Masahiko IgarashiTakeo Kato
Apr 30, 2009·Annual Review of Nutrition·Richard D Mattes
Apr 4, 2021·Nutrients·Ashley N CalderTimothy A Gilbertson
Mar 25, 2006·Physiology & Behavior·M D Robertson
Nov 28, 2006·Biochimie·F LaugeretteP Besnard

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.