Oral health and cardiovascular disease risk in a cohort of periodontitis patients

Atherosclerosis
A HolmlundLars Lind

Abstract

The aim of this study was to determine whether oral health is uniformly associated with three different cardiovascular diseases (CVDs), including myocardial infarction (MI), stroke, and heart failure (HF), which has not been studied previously. A full mouth investigation was performed in 8999 individuals referred to a specialized periodontology clinic between 1979 and 2012. The number of deepened pockets (NDP), number of teeth (NT), and bleeding on probing (BOP) were investigated. Incident CVD diagnosis was obtained from the Swedish cause of death and the hospital discharge registers. During a median follow-up time of 15.8 years (153,103 person years at risk), 1338 incident cases of fatal/non-fatal CVD occurred (672 fatal/non-fatal MI, 545 stroke and 302 HF). When NT, BOP and NDP were all included in the same model with age, sex, smoking, calendar time, and education level, NT and NDP, but not BOP, were significantly related to future CVD (combined end-point, p = 0.0003 for NT and p = 0.007 for NDP). In similar analyses of 3 separate CVD outcomes, NT was significantly related to MI, with an incidence rate ratio (IRR) for a given interquartile range change of 0.90 (95% CI 0.82-0.99) and to HF, with an IRR of 0.87 (95% CI 0.77-0....Continue Reading

Citations

Dec 13, 2018·Hypertension·Davide PietropaoliAnnalisa Monaco
Dec 15, 2019·International Journal of Environmental Research and Public Health·John M NelsonDominic L Palazzolo
Jun 28, 2018·The Journal of the American Osteopathic Association·Lisa SimonChristine Riedy
Mar 27, 2020·International Journal of Mental Health Systems·Amanda KennyNastaran Doroud
Sep 11, 2018·Periodontology 2000·Kenneth S Kornman
May 17, 2019·International Journal of Environmental Research and Public Health·Giancarlo A CuadraDominic L Palazzolo
Feb 21, 2019·Journal of Dental Research·H J LeeS Oh
Oct 31, 2020·Clinical and Experimental Dental Research·Harriet LarvinJianhua Wu
Jan 29, 2021·Clinical Oral Investigations·Viveca Wallin BengtssonStefan Renvert
Feb 18, 2020·Experimental Gerontology·Yifeng QianXudong Wang
Mar 2, 2021·Dental Clinics of North America·Elisa M GhezziJudith A Jones
Feb 2, 2018·The Journal of the American Dental Association·Neel ShimpiAmit Acharya
Apr 19, 2021·The American Journal of Emergency Medicine·Xiaoru QinYuxuan Guo
May 25, 2021·Frontiers in Cardiovascular Medicine·Nicky G F M BeukersGeert J M G van der Heijden

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