[Oral health care by utilizing food function].

Medical Mycology Journal
Yuuki Taguchi

Abstract

We examined the effects of spices and herbs on Candida albicans to develop therapeutic tools against oral diseases such as oral candidiasis. C. albicans, a dimorphic fungus, is a component of the healthy human microbial flora. However, the excessive overgrowth of C. albicans causes oral candidiasis, and the symptoms, accompanied by severe inflammation, reduce the quality of life of elderly people. We found that spices such as clove (Syzygium aromaticum) and cassia (Cinnamomum aromaticum) exhibit inhibitory activity against Candida mycelial growth and show therapeutic efficacy in a murine oral candidiasis model. Our studies also demonstrated that the inhibitory activity of cinnamaldehyde was strengthened in parallel with a prolonged treatment time. Furthermore, when cinnamaldehyde in combination with methylcellulose was administered to the model mice, the therapeutic effect was potentiated. Here, we summarize up-to-date findings on how to use spices and herbs on a daily basis to improve or prevent oral problems such as oral candidiasis with the presentation of our recent data.

References

Aug 7, 1999·Journal of Applied Microbiology·K A HammerT V Riley
Oct 9, 1999·Clinical Microbiology Reviews·M M Cowan
Jul 25, 2003·Antimicrobial Agents and Chemotherapy·Natsuko TakakuraShigeru Abe
Nov 15, 2003·Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology·Shigeru AbeHideyo Yamaguchi
Nov 25, 2003·Diabetes Care·Alam KhanRichard A Anderson
Nov 20, 2004·Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology·Shigeru Abe
Dec 4, 2004·Biological & Pharmaceutical Bulletin·Toshitsugu TaguriIsao Kouno
Feb 16, 2005·Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology·Yuuki TaguchiShigeru Abe
Nov 13, 2008·Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology·Tamaki ChoRichard A Calderone
Jul 25, 2009·Nihon saikingaku zasshi. Japanese journal of bacteriology·Tamaki Cho
Feb 27, 2010·Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology·Yuuki TaguchiShigeru Abe
Apr 14, 2010·International Journal of Food Microbiology·Marziyeh ToloueeMehdi Razzaghi-Abyaneh
Aug 19, 2010·Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology·Kazumi HayamaShigeru Abe
May 3, 2011·Biological & Pharmaceutical Bulletin·Hiroki SasakiTatsuya Morimoto
Nov 15, 2012·Medical Mycology Journal·Yuuki TaguchiShigeru Abe
Jan 18, 2013·Medical Molecular Morphology·Yuuki TaguchiYayoi Nishiyama
May 29, 2013·Journal of Microbiology and Biotechnology·Jonathan W BettsStephen M Kelly
Mar 22, 2014·Biomedical Reports·Chiharu KobaJingo Kusukawa
May 31, 2014·BioMed Research International·Soheil Zorofchian MoghadamtousiKeivan Zandi

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